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NCT04630444 · ClinicalTrials.gov registry record · Early Phase 1
Riluzole Effects on Hippocampus Biomarkers
A Early Phase 1 study, sponsored by Mclean Hospital.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 20
- Enrollment target
NCT04630444: Completed Early Phase 1 study, sponsored by Mclean Hospital.
NCT04630444 is a Early Phase 1 study that has completed, run by Mclean Hospital. The registered enrollment target is 20 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04630444, a Early Phase 1 study, has completed, sponsored by Mclean Hospital.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
To examine the clinical efficacy of the anti-glutamatergic medication riluzole in posttraumatic stress disorder (PTSD), and its effect on hippocampus biomarkers that our laboratory previously has identified using MRS.
Primary Outcome
Testing the hypothesis that riluzole monotherapy will yield within-subject reductions in PTSD total symptoms (CAPS total score)
Interventions
- DRUG Riluzole
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2017-03-16 |
| Est. Completion | 2019-03-16 |
| Phase | Early Phase 1 |
What the finished NCT04630444 record still lists
NCT04630444 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (62% lower).
The record links to 0 conditions, and to 1 intervention - of which Riluzole is the first listed.
NCT04630444 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04630444 about?
NCT04630444 is a clinical study titled "Riluzole Effects on Hippocampus Biomarkers". To examine the clinical efficacy of the anti-glutamatergic medication riluzole in posttraumatic stress disorder (PTSD), and its effect on hippocampus biomarkers that our laboratory previously has identified using MRS.
What is the current status of trial NCT04630444?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 20 participants. The study started on 2017-03-16. Estimated completion is 2019-03-16.
What interventions are being tested in trial NCT04630444?
The interventions under investigation include: Riluzole (DRUG).
Who is sponsoring clinical trial NCT04630444?
This trial is sponsored by Mclean Hospital, which has 140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04630444's enrollment target sits among peer trials
20 1157th of 2000 higher than 710 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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