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NCT04629495 · ClinicalTrials.gov registry record · Phase 2
Rapamycin - Effects on Alzheimer's and Cognitive Health
A Phase 2 study of Alzheimer Disease and Mild Cognitive Impairment, sponsored by The University of Texas Health Science Center at San Antonio.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT04629495: Recruiting Phase 2 study of Alzheimer Disease and Mild Cognitive Impairment, sponsored by The University of Texas Health Science Center at San Antonio.
NCT04629495 is a Phase 2 study of Alzheimer Disease and Mild Cognitive Impairment that is actively recruiting participants, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 40 participants, below the 2,751-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04629495, a Phase 2 study of Alzheimer Disease and Mild Cognitive Impairment, is actively recruiting participants, sponsored by The University of Texas Health Science Center at San Antonio.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will evaluate the safety, tolerability, and feasibility of 12 month oral rapamycin treatment in older adults with amnestic mild cognitive impairment (aMCI) and early stage Alzheimer's disease (AD).
Primary Outcome
Development or worsening of medical symptoms or problems
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Rapamycin
Study Locations (1)
Texas
- Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2021-08-11 |
| Est. Completion | 2026-03 |
| Phase | Phase 2 |
What NCT04629495 shows while recruiting
NCT04629495 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 2,751-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Alzheimer Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04629495 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT04629495 about?
NCT04629495 is a clinical study titled "Rapamycin - Effects on Alzheimer's and Cognitive Health". This study will evaluate the safety, tolerability, and feasibility of 12 month oral rapamycin treatment in older adults with amnestic mild cognitive impairment (aMCI) and early stage Alzheimer's disease (AD).
What is the current status of trial NCT04629495?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2021-08-11. Estimated completion is 2026-03.
What conditions does trial NCT04629495 study?
This clinical trial studies the following conditions: Alzheimer Disease, Mild Cognitive Impairment.
What interventions are being tested in trial NCT04629495?
The interventions under investigation include: Placebo (OTHER), Rapamycin (DRUG).
Who is sponsoring clinical trial NCT04629495?
This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04629495 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alzheimer Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04629495's enrollment target sits among peer trials
40 221st of 306 higher than 74 of 306 other Alzheimer Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alzheimer Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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