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Study to Investigate Safety, Tolerability, PK and PD Response of SLN360 in Subjects With Elevated Lipoprotein(a)
NCT04606602 · View on ClinicalTrials.gov ↗
Study Summary
This study will investigate the safety and tolerability of SLN360 in patients with elevated Lp(a).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG SLN360
Study Locations (8)
Other
- Monash Medical Centre — Clayton
- Amsterdam Medical Centre — Amsterdam
- Hammersmith Medicines Research — London
Florida
- Jacksonville Center for Clinical Research Ltd. — Jacksonville
- Progressive Medical Research — Port Orange
Ohio
- Metabolic and Atherosclerosis Research Center — Cincinnati
- Cleveland Clinic — Cleveland
Western Australia
- Linear Clinical Research — Perth
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2020-11-18 |
| Est. Completion | 2023-08-23 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04606602
The ClinicalTrials.gov registry entry for NCT04606602 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Silence Therapeutics, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Dyslipidemias appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04606602 reports 8 study locations spanning 4 distinct geographic areas — top geographies include Other, Florida, Ohio. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04606602 about?
NCT04606602 is a clinical study titled "Study to Investigate Safety, Tolerability, PK and PD Response of SLN360 in Subjects With Elevated Lipoprotein(a)". This study will investigate the safety and tolerability of SLN360 in patients with elevated Lp(a).
What is the current status of trial NCT04606602?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 70 participants. The study started on 2020-11-18. Estimated completion is 2023-08-23.
What conditions does trial NCT04606602 study?
This clinical trial studies the following conditions: Dyslipidemias, Hyperlipidemias, Elevated Lp(a). These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04606602?
The interventions under investigation include: Placebo (DRUG), SLN360 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04606602?
This trial is sponsored by Silence Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04606602 being conducted?
This trial has 8 study locations across Florida, Ohio, Western Australia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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