Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04604145 · ClinicalTrials.gov registry record · NA

Self-Collected Saliva Samples Without Viral Transport Media for COVID-19 Testing Via RT-PCR

A NA study of SARS-CoV Infection and Polymerase Chain Reaction, sponsored by David Grant U.S. Air Force Medical Center.

Completed
Registry status
NA
Development phase
60
Enrollment target
1
Study location

NCT04604145: Completed NA study of SARS-CoV Infection and Polymerase Chain Reaction, sponsored by David Grant U.S. Air Force Medical Center.

NCT04604145 is a NA study of SARS-CoV Infection and Polymerase Chain Reaction that has completed, run by David Grant U.S. Air Force Medical Center. The registered enrollment target is 60 participants, below the 3,504-participant average among 12 other SARS-CoV Infection trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04604145, a NA study of SARS-CoV Infection and Polymerase Chain Reaction, has completed, sponsored by David Grant U.S. Air Force Medical Center.

COMPLETED
Registry status
NA
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

This is a study that will attempt to validate the process for detecting SARS-CoV-2 (COVID19) on a non-FDA-approved technology using self-collected saliva as the specimen. Investigators will compare self-collected saliva samples and healthcare-worker collected nasopharyngeal samples (Nasal swabs) to see if the self-collected saliva samples are similar in terms of diagnostic accuracy. Investigators will be performing this testing at the site where patients regularly go for COVID19 testing. There will be minimal risk of harm as consenting patients will only have to provide a small amount of saliva into a tube.

Primary Outcome

Percent positive agreement between self-collected saliva samples (evaluated on the Eppendorf Thermal Cycler PCR system) and healthcare-worker collected nasopharyngeal samples (evaluated on either the BioFire® FilmArray® Torch® system or the Cepheid® GeneXpert® as the gold standard).

Interventions

  • DIAGNOSTIC_TEST SARS-CoV-2 testing on the Eppendorf Thermal Cycler PCR system using self-collected saliva as the specimen

Study Locations (1)

California

  • David Grant U.S. Airforce Medical Center - Travis Air Force Base

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2021-02-03
Est. Completion 2021-08-18
Phase NA

What the finished NCT04604145 record still lists

NCT04604145 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 3,504-participant average among 12 other SARS-CoV Infection trials with a reported enrollment target (98% lower).

The record links to 3 conditions, with SARS-CoV Infection appearing as the primary indexed condition, and to 1 intervention - of which SARS-CoV-2 testing on the Eppendorf Thermal Cycler PCR system using self-collected saliva as the specimen is the first listed.

NCT04604145 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT04604145 about?

NCT04604145 is a clinical study titled "Self-Collected Saliva Samples Without Viral Transport Media for COVID-19 Testing Via RT-PCR". This is a study that will attempt to validate the process for detecting SARS-CoV-2 (COVID19) on a non-FDA-approved technology using self-collected saliva as the specimen. Investigators will compare self-collected saliva samples and healthcare-worker collected nasopharyngeal samples (Nasal swabs) to ...

What is the current status of trial NCT04604145?

This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2021-02-03. Estimated completion is 2021-08-18.

What conditions does trial NCT04604145 study?

This clinical trial studies the following conditions: SARS-CoV Infection, Polymerase Chain Reaction, Laboratory Testing.

What interventions are being tested in trial NCT04604145?

The interventions under investigation include: SARS-CoV-2 testing on the Eppendorf Thermal Cycler PCR system using self-collected saliva as the specimen (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT04604145?

This trial is sponsored by David Grant U.S. Air Force Medical Center, which has 21 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04604145 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for SARS-CoV Infection

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04604145's enrollment target sits among peer trials

60 12th of 12 higher than 1 of 12 other SARS-CoV Infection trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other SARS-CoV Infection trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00576069 · 60 participants

    Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma

  • NCT01297400 · 60 participants · Phase 2

    Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns

  • NCT01734122 · 60 participants

    Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

  • NCT01804634 · 60 participants · Phase 2

    Reduced Intensity Haploidentical BMT for High Risk Solid Tumors

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04604145, the US trial registry maintained by the National Library of Medicine. NCT04604145 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.