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NCT04590040 · ClinicalTrials.gov registry record · NA
Trial of Nano-hydroxyapatite-Containing Toothpastes for Relief of Dentin Hypersensitivity
A NA study, sponsored by The University of Texas Health Science Center at San Antonio.
- Completed
- Registry status
- NA
- Development phase
- 192
- Enrollment target
NCT04590040: Completed NA study, sponsored by The University of Texas Health Science Center at San Antonio.
NCT04590040 is a NA study that has completed, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 192 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04590040, a NA study, has completed, sponsored by The University of Texas Health Science Center at San Antonio.
- COMPLETED
- Registry status
- NA
- Development phase
- 192 participants
- Enrollment target
Study Summary
Subjects will be enrolled into 3 balanced groups each using a different strength toothpaste. Dental hypersensitivity (DHS) will be assessed at study start, midway and study end.
Primary Outcome
The primary efficacy outcome will be the decrease in cold air stimulus sensitivity (VAS score) from baseline to 8 weeks. Assessment of change in cold air sensitivity will be conducted using air delivered from a standard dental unit air syringe at room temperature (\~70°F±3°F)(\~21°C±2°C) and a pressure of 60psi (± 5psi). Assessment of sensitivity will be carried out using Visual Analog Scale (VAS). Tooth sensitivity was measured using a Cold Air Stimulus. When being assessed, participants rated
Interventions
- OTHER Placebo
- DEVICE 15% nano-HAP toothpaste
- DEVICE 5% KNO3 toothpaste
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 192 participants |
| Start Date | 2020-07-28 |
| Est. Completion | 2023-03-01 |
| Phase | NA |
What the finished NCT04590040 record still lists
NCT04590040 is an interventional study that assigns participants to a tested intervention. The registered 192 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT04590040 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04590040 about?
NCT04590040 is a clinical study titled "Trial of Nano-hydroxyapatite-Containing Toothpastes for Relief of Dentin Hypersensitivity". Subjects will be enrolled into 3 balanced groups each using a different strength toothpaste. Dental hypersensitivity (DHS) will be assessed at study start, midway and study end.
What is the current status of trial NCT04590040?
This trial is currently completed. It is a NA study. The enrollment target is 192 participants. The study started on 2020-07-28. Estimated completion is 2023-03-01.
What interventions are being tested in trial NCT04590040?
The interventions under investigation include: Placebo (OTHER), 15% nano-HAP toothpaste (DEVICE), 5% KNO3 toothpaste (DEVICE).
Who is sponsoring clinical trial NCT04590040?
This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04590040's enrollment target sits among peer trials
192 570th of 2000 higher than 1,427 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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