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NCT04586959 · ClinicalTrials.gov registry record · NA
Uterine Manipulation During Minimally Invasive Surgery for Early Stage Endometrial Cancer
A NA study of Endometrial Cancer, sponsored by Anthony Costales, MD.
- Recruiting
- Registry status
- NA
- Development phase
- 278
- Enrollment target
- 5
- Study locations
NCT04586959: Recruiting NA study of Endometrial Cancer, sponsored by Anthony Costales, MD.
NCT04586959 is a NA study of Endometrial Cancer that is actively recruiting participants, run by Anthony Costales, MD. The registered enrollment target is 278 participants, below the 522-participant average among 181 other Endometrial Cancer trials with a reported enrollment target (47% lower). The trial reports 5 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04586959, a NA study of Endometrial Cancer, is actively recruiting participants, sponsored by Anthony Costales, MD.
- RECRUITING
- Registry status
- NA
- Development phase
- 278 participants
- Enrollment target
- 5
- Study locations
Study Summary
This is a prospective, multi-center, randomized non-inferiority phase III study to evaluate if patients undergoing a minimally invasive surgery for early stage uterine cancer have cancer cells in the fluid that is obtained at the time of their surgery when a uterine manipulator is placed versus patients who do not have a uterine manipulator placed.
Primary Outcome
Positive PC is defined as the presence of malignant cells in the peritoneal cytology specimen.
Conditions Studied
Interventions
- DEVICE Surgery with UM
- DEVICE Surgery without UM
Study Locations (5)
Texas
- Baylor College of Medicine- McNair Campus - Houston
- Baylor College of Medicine - Houston
- Ben Taub General Hospital - Houston
- Harris Health System - Smith Clinic - Houston
Ohio
- Cleveland Clinic - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 278 participants |
| Start Date | 2021-05-21 |
| Est. Completion | 2027-10 |
| Phase | NA |
What NCT04586959 shows while recruiting
NCT04586959 is an interventional study that assigns participants to a tested intervention. The registered 278 participants enrollment target is mid-sized for trials with a published cap, below the 522-participant average among 181 other Endometrial Cancer trials with a reported enrollment target (47% lower).
The record links to 1 condition, with Endometrial Cancer appearing as the primary indexed condition, and to 2 interventions - of which Surgery with UM is the first listed.
NCT04586959 lists 5 locations in 2 states (Texas, Ohio).
Frequently Asked Questions
What is clinical trial NCT04586959 about?
NCT04586959 is a clinical study titled "Uterine Manipulation During Minimally Invasive Surgery for Early Stage Endometrial Cancer". This is a prospective, multi-center, randomized non-inferiority phase III study to evaluate if patients undergoing a minimally invasive surgery for early stage uterine cancer have cancer cells in the fluid that is obtained at the time of their surgery when a uterine manipulator is placed versus pati...
What is the current status of trial NCT04586959?
This trial is currently recruiting. It is a NA study. The enrollment target is 278 participants. The study started on 2021-05-21. Estimated completion is 2027-10.
What conditions does trial NCT04586959 study?
This clinical trial studies the following conditions: Endometrial Cancer.
What interventions are being tested in trial NCT04586959?
The interventions under investigation include: Surgery with UM (DEVICE), Surgery without UM (DEVICE).
Who is sponsoring clinical trial NCT04586959?
This trial is sponsored by Anthony Costales, MD, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04586959 being conducted?
This trial has 5 study locations across Ohio, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Endometrial Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04586959's enrollment target sits among peer trials
278 47th of 181 higher than 135 of 181 other Endometrial Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Endometrial Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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ctDNA Testing to Inform Standard-of-Care Treatment Decisions in People With Endometrial Cancer
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Use of an Intrauterine Manipulator and Its Correlation with Positive Peritoneal Cytology in Early Stage Endometrial Cancers
RECRUITING · NA
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