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NCT04586699 · ClinicalTrials.gov registry record · NA

Meditation Accelerated Brain Stimulation for Depression

A NA study of Depression, sponsored by University of California, San Diego.

Active
Registry status
NA
Development phase
50
Enrollment target
2
Study locations

NCT04586699 is a NA study of Depression that is active but no longer recruiting, run by University of California, San Diego. The registered enrollment target is 50 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (94% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT04586699, a NA study of Depression, is active but no longer recruiting, sponsored by University of California, San Diego.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
50 participants
Enrollment target
2
Study locations

Study Summary

Repetitive Transcranial magnetic stimulation (rTMS) is an FDA-approved treatment for depression that involves brief magnetic stimulation pulses on the dorsolateral prefrontal cortex (DLPFC) brain region. The ultimate goal of this treatment is to increase excitability and long-term plasticity in DLPFC, a brain region shown to be hypo-active in depression. Unfortunately, rTMS only has low to moderate efficacy; remission rates for patients range from \~15-30% in large randomized controlled trials. The focus of this research is to develop a next-generation rTMS protocol that is guided by the basic principles underlying brain plasticity, in order to improve the efficacy of rTMS for the treatment of depression. Specifically, in this study the investigators will test rTMS paired with a depression-relevant cognitive state of internal attention.

Conditions Studied

Depression

Interventions

  • DEVICE Medi1TMS
  • DEVICE Medi2TMS

Study Locations (2)

California

  • Neuromodulation Clinic Veterans Affairs San Diego - San Diego
  • UC San Diego Health Psychiatry - San Diego

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2021-07-15
Est. Completion 2026-06-30
Phase NA

Sponsor

University of California, San Diego

775 total trials

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What the Registry Record Tells You About NCT04586699

The ClinicalTrials.gov registry entry for NCT04586699 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (94% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Medi1TMS is the first listed.

NCT04586699 reports 2 study locations spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT04586699 about?

NCT04586699 is a clinical study titled "Meditation Accelerated Brain Stimulation for Depression". Repetitive Transcranial magnetic stimulation (rTMS) is an FDA-approved treatment for depression that involves brief magnetic stimulation pulses on the dorsolateral prefrontal cortex (DLPFC) brain region. The ultimate goal of this treatment is to increase excitability and long-term plasticity in DLPF...

What is the current status of trial NCT04586699?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2021-07-15. Estimated completion is 2026-06-30.

What conditions does trial NCT04586699 study?

This clinical trial studies the following conditions: Depression.

What interventions are being tested in trial NCT04586699?

The interventions under investigation include: Medi1TMS (DEVICE), Medi2TMS (DEVICE).

Who is sponsoring clinical trial NCT04586699?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04586699 being conducted?

This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.