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NCT04582682 · ClinicalTrials.gov registry record
Poly-omic Predictors of Symptom Duration and Recovery for Adolescent Concussion
A clinical trial of Concussion, Mild, sponsored by Milton S. Hershey Medical Center.
- Active
- Registry status
- 750
- Enrollment target
- 5
- Study locations
NCT04582682: Active study of Concussion, Mild, sponsored by Milton S. Hershey Medical Center.
NCT04582682 is a study of Concussion, Mild that is active but no longer recruiting, run by Milton S. Hershey Medical Center. The registered enrollment target is 750 participants, above the 162-participant average among 18 other Concussion, Mild trials with a reported enrollment target (363% higher). The trial reports 5 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04582682, a study of Concussion, Mild, is active but no longer recruiting, sponsored by Milton S. Hershey Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- 750 participants
- Enrollment target
- 5
- Study locations
Study Summary
The purpose of this study is to identify changes in salivary micro ribonucleic acid (miRNA) levels that are predictive of symptom duration and character following mild traumatic brain injury (mTBI) in children.
Primary Outcome
PPCS will be defined by persistence of at least 3 symptoms on day 30, compared with pre-injury state, which will be determined from pre-injury symptoms reported at enrollment using the Post-Concussion Symptom Inventory (PCSI). PCSI is a self reported survey that focus on symptoms in the cognitive, emotional, sleep, and physical domains. This form is called the "Sport Concussion Assessment Tool- 5th Edition" and symptoms are scored from 0 to 6 with 0 being no symptom and 6 being severe. A high sc
Conditions Studied
Study Locations (5)
New York
- Weill Cornell Medicine/ New York Presbyterian Hospital - New York
- SUNY Upstate Medical University - Syracuse
Massachusetts
- Boston Children's Hosptial - Boston
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
Pennsylvania
- Penn State Milton S. Hershey Medical Center - Hershey
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 750 participants |
| Start Date | 2021-01-18 |
| Est. Completion | 2026-06 |
What the registry record for NCT04582682 still lists
NCT04582682 is an observational study that tracks outcomes without assigning an intervention. The registered 750 participants enrollment target is mid-sized for trials with a published cap, above the 162-participant average among 18 other Concussion, Mild trials with a reported enrollment target (363% higher).
The record links to 1 condition, with Concussion, Mild appearing as the primary indexed condition, and to 0 interventions.
NCT04582682 lists 5 locations in 4 states (New York, Massachusetts, Ohio).
Frequently Asked Questions
What is clinical trial NCT04582682 about?
NCT04582682 is a clinical study titled "Poly-omic Predictors of Symptom Duration and Recovery for Adolescent Concussion". The purpose of this study is to identify changes in salivary micro ribonucleic acid (miRNA) levels that are predictive of symptom duration and character following mild traumatic brain injury (mTBI) in children.
What is the current status of trial NCT04582682?
This trial is currently active not recruiting. The enrollment target is 750 participants. The study started on 2021-01-18. Estimated completion is 2026-06.
What conditions does trial NCT04582682 study?
This clinical trial studies the following conditions: Concussion, Mild.
Who is sponsoring clinical trial NCT04582682?
This trial is sponsored by Milton S. Hershey Medical Center, which has 396 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04582682 being conducted?
This trial has 5 study locations across Massachusetts, New York, Ohio, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04582682's enrollment target sits among peer trials
750 1st of 18 higher than 18 of 18 other Concussion, Mild trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Concussion, Mild trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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