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NCT04581902 · ClinicalTrials.gov registry record · NA
Biomarkers of Depression and Treatment Response
A NA study of Depressive Disorder, Major, sponsored by University of California, San Francisco.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT04581902: Recruiting NA study of Depressive Disorder, Major, sponsored by University of California, San Francisco.
NCT04581902 is a NA study of Depressive Disorder, Major that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 50 participants, below the 241-participant average among 52 other Depressive Disorder, Major trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04581902, a NA study of Depressive Disorder, Major, is actively recruiting participants, sponsored by University of California, San Francisco.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is a stratified, parallel-group, single-center study utilizing multimodal imaging techniques to identify biomarkers for Major Depressive Disorder (MDD). The study goal is to identify biomarkers for MDD and treatment response that can be implemented in clinical diagnosis and care as valid and reliable measures, through monitoring neurophysiological and electrophysiological changes across the course of transcranial magnetic stimulation (TMS) treatment.
Primary Outcome
Effect size of active stimulation (mean difference in Montgomery Asberg Depression Rating Scale (MADRS) score) before and after morning and afternoon treatment course. Higher MADRS score indicates more severe depression; the overall score ranges from 0 to 60.
Conditions Studied
Interventions
- DEVICE rTMS therapy
Study Locations (1)
California
- University of California, San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2020-12-01 |
| Est. Completion | 2027-09 |
| Phase | NA |
What NCT04581902 shows while recruiting
NCT04581902 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 241-participant average among 52 other Depressive Disorder, Major trials with a reported enrollment target (79% lower).
The record links to 1 condition, with Depressive Disorder, Major appearing as the primary indexed condition, and to 1 intervention - of which rTMS therapy is the first listed.
NCT04581902 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04581902 about?
NCT04581902 is a clinical study titled "Biomarkers of Depression and Treatment Response". This study is a stratified, parallel-group, single-center study utilizing multimodal imaging techniques to identify biomarkers for Major Depressive Disorder (MDD). The study goal is to identify biomarkers for MDD and treatment response that can be implemented in clinical diagnosis and care as valid ...
What is the current status of trial NCT04581902?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2020-12-01. Estimated completion is 2027-09.
What conditions does trial NCT04581902 study?
This clinical trial studies the following conditions: Depressive Disorder, Major.
What interventions are being tested in trial NCT04581902?
The interventions under investigation include: rTMS therapy (DEVICE).
Who is sponsoring clinical trial NCT04581902?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04581902 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depressive Disorder, Major
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04581902's enrollment target sits among peer trials
50 37th of 52 higher than 14 of 52 other Depressive Disorder, Major trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depressive Disorder, Major trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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