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NCT04580745 · ClinicalTrials.gov registry record · Phase 1

Study of MORF 057 to Evaluate Single and Multi Ascending Doses in Healthy Volunteers

A Phase 1 study of Healthy Volunteers, sponsored by Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company).

Completed
Registry status
Phase 1
Development phase
67
Enrollment target
1
Study location

NCT04580745: Completed Phase 1 study of Healthy Volunteers, sponsored by Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company).

NCT04580745 is a Phase 1 study of Healthy Volunteers that has completed, run by Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company). The registered enrollment target is 67 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04580745, a Phase 1 study of Healthy Volunteers, has completed, sponsored by Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company).

COMPLETED
Registry status
Phase 1
Development phase
67 participants
Enrollment target
1
Study location

Study Summary

Phase 1a randomized, double-blind, placebo-controlled study to evaluate single and multiple ascending doses of MORF-057 in healthy subjects.

Primary Outcome

Subject incidence of adverse events and serious adverse events

Conditions Studied

Interventions

  • DRUG MORF-057
  • DRUG Placebo for MORF-057

Study Locations (1)

Ohio

  • Medpace - Cincinnati

Trial Details

FieldValue
Enrollment Target 67 participants
Start Date 2020-09-23
Est. Completion 2021-04-12
Phase Phase 1

What the finished NCT04580745 record still lists

NCT04580745 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 67 participants, a relatively small participant target, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (86% lower).

The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 2 interventions - of which MORF-057 is the first listed.

NCT04580745 reports a single indexed study location in Ohio.

Frequently Asked Questions

What is clinical trial NCT04580745 about?

NCT04580745 is a clinical study titled "Study of MORF 057 to Evaluate Single and Multi Ascending Doses in Healthy Volunteers". Phase 1a randomized, double-blind, placebo-controlled study to evaluate single and multiple ascending doses of MORF-057 in healthy subjects.

What is the current status of trial NCT04580745?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 67 participants. The study started on 2020-09-23. Estimated completion is 2021-04-12.

What conditions does trial NCT04580745 study?

This clinical trial studies the following conditions: Healthy Volunteers.

What interventions are being tested in trial NCT04580745?

The interventions under investigation include: MORF-057 (DRUG), Placebo for MORF-057 (DRUG).

Who is sponsoring clinical trial NCT04580745?

This trial is sponsored by Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company), which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04580745 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Volunteers

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04580745's enrollment target sits among peer trials

67 99th of 283 higher than 184 of 283 other Healthy Volunteers trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04580745, the US trial registry maintained by the National Library of Medicine. NCT04580745 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.