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NCT04544098 · ClinicalTrials.gov registry record · Early Phase 1

Lutathera in People With Gastroenteropancreatic (GEP), Bronchial or Unknown Primary Neuroendocrine Tumors That Have Spread to the Liver

A Early Phase 1 study of Neuroendocrine Tumors and Liver-Dominant Metastatic Pancreatic Neuroendocrine Tumors, sponsored by Memorial Sloan Kettering Cancer Center.

Active
Registry status
Early Phase 1
Development phase
10
Enrollment target
1
Study location

NCT04544098 is a Early Phase 1 study of Neuroendocrine Tumors and Liver-Dominant Metastatic Pancreatic Neuroendocrine Tumors that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 10 participants, below the 180-participant average among 52 other Neuroendocrine Tumors trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04544098, a Early Phase 1 study of Neuroendocrine Tumors and Liver-Dominant Metastatic Pancreatic Neuroendocrine Tumors, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Early Phase 1
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

This study will look at whether it is practical and safe to give Lutathera directly into an artery of the liver (hepatic intraarterial infusion). The researchers will compare the effects of hepatic intraarterial infusion in the liver with the effects of the standard approach (intravenous infusion in the arm). The researchers will also determine whether Lutathera is effective against participants' cancer.

Interventions

  • DRUG 177Lu-DOTATATE

Study Locations (1)

New York

  • Memorial Sloan Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2020-09-02
Est. Completion 2026-09
Phase Early Phase 1

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT04544098

The ClinicalTrials.gov registry entry for NCT04544098 describes a study currently listed as active not recruiting, categorized as Early Phase 1. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 180-participant average among 52 other Neuroendocrine Tumors trials with a reported enrollment target (94% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Neuroendocrine Tumors appearing as the primary indexed condition, and to 1 intervention - of which 177Lu-DOTATATE is the first listed.

NCT04544098 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT04544098 about?

NCT04544098 is a clinical study titled "Lutathera in People With Gastroenteropancreatic (GEP), Bronchial or Unknown Primary Neuroendocrine Tumors That Have Spread to the Liver". This study will look at whether it is practical and safe to give Lutathera directly into an artery of the liver (hepatic intraarterial infusion). The researchers will compare the effects of hepatic intraarterial infusion in the liver with the effects of the standard approach (intravenous infusion in...

What is the current status of trial NCT04544098?

This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 10 participants. The study started on 2020-09-02. Estimated completion is 2026-09.

What conditions does trial NCT04544098 study?

This clinical trial studies the following conditions: Neuroendocrine Tumors, Liver-Dominant Metastatic Pancreatic Neuroendocrine Tumors.

What interventions are being tested in trial NCT04544098?

The interventions under investigation include: 177Lu-DOTATATE (DRUG).

Who is sponsoring clinical trial NCT04544098?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04544098 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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