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NCT04543461 · ClinicalTrials.gov registry record
American Lung Association (ALA) Lung Health Cohort
A clinical trial of Lung Diseases, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- 4,000
- Enrollment target
- 20
- Study locations
NCT04543461: Recruiting study of Lung Diseases, sponsored by Johns Hopkins University.
NCT04543461 is a study of Lung Diseases that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 4,000 participants, above the 611-participant average among 31 other Lung Diseases trials with a reported enrollment target (555% higher). The trial reports 20 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04543461, a study of Lung Diseases, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- 4,000 participants
- Enrollment target
- 20
- Study locations
Study Summary
The ALA-LHC is a longitudinal, multi-center cohort study that will enroll approximately 4,000 young adults between the ages of 25-35 who do not have severe lung disease. The overarching objective of the ALA-LHC is to establish a national cohort of young adults for the purpose of defining lung health and developing targets to intercept chronic lung disease at its earliest stages.
Primary Outcome
Pre-bronchodilator measurements of FEV1 to determine bronchoconstriction. FEV1 is measured in liters of air. Severity of bronchoconstriction is based on predicted values published by National Health and Nutrition Examination Survey (NHANES III hankinson) for height, weight and age. Predicted values are reported as percent predicted with a result of 80% or greater considered normal
Conditions Studied
Study Locations (20)
Illinois
- University of Illinois at Chicago - Chicago
- Northwestern University - Chicago
- Rush Universtiy - Chicago
- University of Chicago - Chicago
California
- University of California, Los Angeles - Los Angeles
- University of California, San Francisco - San Francisco
Colorado
- University of Colorado - Aurora
- National Jewish Health - Denver
Florida
- Nemours Children's Jacksonville - Jacksonville
- University of Florida, Jacksonville - Jacksonville
New York
- Presbyterian Brooklyn Methodist Hospital - Brooklyn
- New York Medical College - Hawthorne
Alabama
- University Of Alabama - Birmingham
Arizona
- University of Arizona-Tuscon - Tucson
Indiana
- St. Vincent's Health System - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4,000 participants |
| Start Date | 2021-10-29 |
| Est. Completion | 2026-09 |
What NCT04543461 shows while recruiting
NCT04543461 is an observational study that tracks outcomes without assigning an intervention. Its 4,000 participants enrollment target places it among the larger protocols in the corpus, above the 611-participant average among 31 other Lung Diseases trials with a reported enrollment target (555% higher).
The record links to 1 condition, with Lung Diseases appearing as the primary indexed condition, and to 0 interventions.
NCT04543461 names 20 study sites across 13 states, led by Illinois, California, Colorado.
Frequently Asked Questions
What is clinical trial NCT04543461 about?
NCT04543461 is a clinical study titled "American Lung Association (ALA) Lung Health Cohort". The ALA-LHC is a longitudinal, multi-center cohort study that will enroll approximately 4,000 young adults between the ages of 25-35 who do not have severe lung disease. The overarching objective of the ALA-LHC is to establish a national cohort of young adults for the purpose of defining lung health...
What is the current status of trial NCT04543461?
This trial is currently recruiting. The enrollment target is 4,000 participants. The study started on 2021-10-29. Estimated completion is 2026-09.
What conditions does trial NCT04543461 study?
This clinical trial studies the following conditions: Lung Diseases.
Who is sponsoring clinical trial NCT04543461?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04543461 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Lung Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04543461's enrollment target sits among peer trials
4,000 1st of 31 the highest of 31 other Lung Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lung Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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