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NCT00747227 · ClinicalTrials.gov registry record · Phase 3

Safety and Efficacy of a Violet Visible Light Blocking Intraocular Lens (IOL)

A Phase 3 study of Cataract, sponsored by Abbott Medical Optics.

Completed
Registry status
Phase 3
Development phase
250
Enrollment target
11
Study locations

NCT00747227: Completed Phase 3 study of Cataract, sponsored by Abbott Medical Optics.

NCT00747227 is a Phase 3 study of Cataract that has completed, run by Abbott Medical Optics. The registered enrollment target is 250 participants, above the 225-participant average among 83 other Cataract trials with a reported enrollment target (11% higher). The trial reports 11 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00747227, a Phase 3 study of Cataract, has completed, sponsored by Abbott Medical Optics.

COMPLETED
Registry status
Phase 3
Development phase
250 participants
Enrollment target
11
Study locations

Study Summary

The purpose of this study is to evaluate the safety and effectiveness of a new investigational modified light transmission monofocal intraocular lens compared to a conventional intraocular lens (IOL).

Primary Outcome

Snellen Equivalent visual acuity of 20/40 or better

Conditions Studied

Interventions

  • DEVICE modified light transmission intraocular lens
  • DEVICE monofocal acrylic intraocular lens

Study Locations (11)

Pennsylvania

  • William Christie, M.D. - Cranberry Township
  • Mark Blecher, M.D. - Philadelphia

Arizona

  • Patrick Aiello, M.D. - Scottsdale

Arkansas

  • Randall E. Cole, M.D. - Rogers

Connecticut

  • Aron Rose, M.D. - New Haven

Minnesota

  • Y. Ralph Chu, M.D. - Bloomington

Missouri

  • Steven Silverstein, M.D. - Kansas City

Oregon

  • Jon-Marc Weston, M.D. - Roseburg

Rhode Island

  • Robert L. Bahr, M.D. - Providence

Trial Details

FieldValue
Enrollment Target 250 participants
Start Date 2006-12
Est. Completion 2009-06
Phase Phase 3
Abbott Medical Optics

14 total trials

What the finished NCT00747227 record still lists

NCT00747227 is an interventional study that assigns participants to a tested intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap, above the 225-participant average among 83 other Cataract trials with a reported enrollment target (11% higher).

The record links to 1 condition, with Cataract appearing as the primary indexed condition, and to 2 interventions - of which modified light transmission intraocular lens is the first listed.

NCT00747227 lists 11 locations in 10 states (Pennsylvania, Arizona, Arkansas).

Frequently Asked Questions

What is clinical trial NCT00747227 about?

NCT00747227 is a clinical study titled "Safety and Efficacy of a Violet Visible Light Blocking Intraocular Lens (IOL)". The purpose of this study is to evaluate the safety and effectiveness of a new investigational modified light transmission monofocal intraocular lens compared to a conventional intraocular lens (IOL).

What is the current status of trial NCT00747227?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 250 participants. The study started on 2006-12. Estimated completion is 2009-06.

What conditions does trial NCT00747227 study?

This clinical trial studies the following conditions: Cataract.

What interventions are being tested in trial NCT00747227?

The interventions under investigation include: modified light transmission intraocular lens (DEVICE), monofocal acrylic intraocular lens (DEVICE).

Who is sponsoring clinical trial NCT00747227?

This trial is sponsored by Abbott Medical Optics, which has 14 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00747227 being conducted?

This trial has 11 study locations across Arizona, Arkansas, Connecticut, Minnesota, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cataract

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00747227's enrollment target sits among peer trials

250 21st of 83 higher than 62 of 83 other Cataract trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cataract trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00747227, the US trial registry maintained by the National Library of Medicine. NCT00747227 (mid enrollment · multi site footprint · completed) retrieved and formatted by PlainTrial, see methodology.