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NCT04539470 · ClinicalTrials.gov registry record · Phase 1

Study to Evaluate the Safety and Pharmacokinetics of Efmarodocokin Alfa in Combination With Standard of Care in Participants Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

A Phase 1 study, sponsored by Genentech.

Completed
Registry status
Phase 1
Development phase
18
Enrollment target

NCT04539470 is a Phase 1 study that has completed, run by Genentech. The registered enrollment target is 18 participants.

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The verdict

NCT04539470, a Phase 1 study, has completed, sponsored by Genentech.

COMPLETED
Registry status
Phase 1
Development phase
18 participants
Enrollment target

Study Summary

This is a Phase Ib, open-label, multicenter, dose-escalation study to evaluate the safety, tolerability, and pharmacokinetics of Efmarodocokin Alfa and to make a preliminary assessment of activity of Efmarodocokin Alfa in combination with standard-of-care (SOC) in the prevention of acute graft-versus-host disease (aGVHD) in participants undergoing allogeneic hematopoietic stem cell transplantation (HSCT).

Interventions

  • DRUG Efmarodocokin Alfa

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2020-11-19
Est. Completion 2023-02-24
Phase Phase 1

Sponsor

Genentech

332 total trials

What the Registry Record Tells You About NCT04539470

The ClinicalTrials.gov registry entry for NCT04539470 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Efmarodocokin Alfa is the first listed.

NCT04539470 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04539470 about?

NCT04539470 is a clinical study titled "Study to Evaluate the Safety and Pharmacokinetics of Efmarodocokin Alfa in Combination With Standard of Care in Participants Undergoing Allogeneic Hematopoietic Stem Cell Transplantation". This is a Phase Ib, open-label, multicenter, dose-escalation study to evaluate the safety, tolerability, and pharmacokinetics of Efmarodocokin Alfa and to make a preliminary assessment of activity of Efmarodocokin Alfa in combination with standard-of-care (SOC) in the prevention of acute graft-versu...

What is the current status of trial NCT04539470?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2020-11-19. Estimated completion is 2023-02-24.

What interventions are being tested in trial NCT04539470?

The interventions under investigation include: Efmarodocokin Alfa (DRUG).

Who is sponsoring clinical trial NCT04539470?

This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.