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NCT04533555 · ClinicalTrials.gov registry record · NA
Genetic Testing in Young Adults With Cancer Study
A NA study of Cancer, sponsored by University of Pennsylvania.
- Completed
- Registry status
- NA
- Development phase
- 749
- Enrollment target
- 1
- Study location
NCT04533555: Completed NA study of Cancer, sponsored by University of Pennsylvania.
NCT04533555 is a NA study of Cancer that has completed, run by University of Pennsylvania. The registered enrollment target is 749 participants, below the 3,490-participant average among 615 other Cancer trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04533555, a NA study of Cancer, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- NA
- Development phase
- 749 participants
- Enrollment target
- 1
- Study location
Study Summary
The overarching goal of our research is to define an evidence-based, sustainable approach to identifying and managing genetic risk among young adults with cancer and their relatives. Conventional practice leaves referral and testing decisions to mostly non-expert clinicians implementing complex guidelines at the point of care, leading to substantial under-utilization. The investigators hypothesize that panel-based universal screening coupled with electronic medical record- (EMR-) based algorithms can improve ascertainment of genetic risk by functioning as an automated, radically simplified default practice in place of repeated single decisions requiring clinician cognitive effort and action. A secondary goal is to explore differences in ascertainment of genetic risk among first-degree relatives of probands.
Primary Outcome
comparison of proportions of patients with P/LP germline variants between the two study arms
Conditions Studied
Interventions
- GENETIC Broad gene panel for young adult cancers
- GENETIC Standard
Study Locations (1)
Pennsylvania
- University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 749 participants |
| Start Date | 2020-12-01 |
| Est. Completion | 2025-09-26 |
| Phase | NA |
What the finished NCT04533555 record still lists
NCT04533555 is an interventional study that assigns participants to a tested intervention. The registered 749 participants enrollment target is mid-sized for trials with a published cap, below the 3,490-participant average among 615 other Cancer trials with a reported enrollment target (79% lower).
The record links to 1 condition, with Cancer appearing as the primary indexed condition, and to 2 interventions - of which Broad gene panel for young adult cancers is the first listed.
NCT04533555 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT04533555 about?
NCT04533555 is a clinical study titled "Genetic Testing in Young Adults With Cancer Study". The overarching goal of our research is to define an evidence-based, sustainable approach to identifying and managing genetic risk among young adults with cancer and their relatives. Conventional practice leaves referral and testing decisions to mostly non-expert clinicians implementing complex guid...
What is the current status of trial NCT04533555?
This trial is currently completed. It is a NA study. The enrollment target is 749 participants. The study started on 2020-12-01. Estimated completion is 2025-09-26.
What conditions does trial NCT04533555 study?
This clinical trial studies the following conditions: Cancer.
What interventions are being tested in trial NCT04533555?
The interventions under investigation include: Broad gene panel for young adult cancers (GENETIC), Standard (GENETIC).
Who is sponsoring clinical trial NCT04533555?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04533555 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04533555's enrollment target sits among peer trials
749 96th of 615 higher than 520 of 615 other Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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