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NCT04532749 · ClinicalTrials.gov registry record · Phase 3

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

A Phase 3 study, sponsored by Janssen Research & Development.

Terminated
Registry status
Phase 3
Development phase
212
Enrollment target

NCT04532749 is a Phase 3 study that was terminated before completion, run by Janssen Research & Development. The registered enrollment target is 212 participants.

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The verdict

NCT04532749, a Phase 3 study, was terminated before completion, sponsored by Janssen Research & Development.

TERMINATED
Registry status
Phase 3
Development phase
212 participants
Enrollment target

Study Summary

The purpose of this study is to assess the efficacy of Seltorexant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in participants with major depressive disorder with insomnia symptoms (MDDIS) who have had an inadequate response to current antidepressant therapy with a selective serotonin reuptake inhibitor (SSRI) or serotonin-norepinephrine reuptake inhibitor (SNRI).

Interventions

  • DRUG Placebo
  • DRUG Seltorexant

Trial Details

FieldValue
Enrollment Target 212 participants
Start Date 2020-09-15
Est. Completion 2022-07-14
Phase Phase 3

Sponsor

Janssen Research & Development

593 total trials

What the Registry Record Tells You About NCT04532749

The ClinicalTrials.gov registry entry for NCT04532749 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 212 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 593 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04532749 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04532749 about?

NCT04532749 is a clinical study titled "A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy". The purpose of this study is to assess the efficacy of Seltorexant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in participants with major depressive disorder with insomnia symptoms (MDDIS) who have had an inadequate response to current antidepres...

What is the current status of trial NCT04532749?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 212 participants. The study started on 2020-09-15. Estimated completion is 2022-07-14.

What interventions are being tested in trial NCT04532749?

The interventions under investigation include: Placebo (DRUG), Seltorexant (DRUG).

Who is sponsoring clinical trial NCT04532749?

This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.