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NCT04513782 · ClinicalTrials.gov registry record

The Contributions of Age Related Changes in the Sound Localization Pathway to Central Hearing Loss

A clinical trial of Healthy Individuals and Hearing Loss, Central, sponsored by University of Colorado, Denver.

Recruiting
Registry status
200
Enrollment target
1
Study location

NCT04513782 is a study of Healthy Individuals and Hearing Loss, Central that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 200 participants, above the 58-participant average among 3 other Healthy Individuals trials with a reported enrollment target (245% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT04513782, a study of Healthy Individuals and Hearing Loss, Central, is actively recruiting participants, sponsored by University of Colorado, Denver.

RECRUITING
Registry status
200 participants
Enrollment target
1
Study location

Study Summary

Age-related hearing loss, presbycusis, affects up to 50% of American adults. There are two main causes for presbycusis: 1) Progressive death of hair cells in the inner ear, and 2) Central hearing loss, or the reduced ability to decipher the sound source of interest from other competing sounds in a multi-source complex environment. The first cause is better understood and treatment options, such as hearing aids and cochlear implants, are available. However, central hearing loss is not as well understood and there is not a treatment available at this time. This study aims to advance our understanding of central hearing loss by evaluating the abilities of younger and older listeners in two primary outcome measures: to 1) neurologically process sound stimuli and 2) focus on conversational speech in the presence of spatially-separated competing background noise. A test using Auditory Brainstem Responses (ABR) will be used to evaluate the brain's response to clicking sounds. This study will assess all waveform data, but will focus particularly on wave III. Sentence in noise tests will be used to assess each subject's ability to process speech in noisy situations. Both the ABR and sentence in noise tests are non-invasive and are commonly used in audiology practices to diagnosis and treat a variety of audiological pathologies.

Interventions

  • DIAGNOSTIC_TEST Audiological Assessments

Study Locations (1)

Colorado

  • University of Colorado School of Medicine - Aurora

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2020-10-01
Est. Completion 2026-05-29

Sponsor

University of Colorado, Denver

1,283 total trials

What the Registry Record Tells You About NCT04513782

The ClinicalTrials.gov registry entry for NCT04513782 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 58-participant average among 3 other Healthy Individuals trials with a reported enrollment target (245% higher). The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Healthy Individuals appearing as the primary indexed condition, and to 1 intervention - of which Audiological Assessments is the first listed.

NCT04513782 reports 1 study location spanning 1 distinct geographic area - top geographies include Colorado.

Frequently Asked Questions

What is clinical trial NCT04513782 about?

NCT04513782 is a clinical study titled "The Contributions of Age Related Changes in the Sound Localization Pathway to Central Hearing Loss". Age-related hearing loss, presbycusis, affects up to 50% of American adults. There are two main causes for presbycusis: 1) Progressive death of hair cells in the inner ear, and 2) Central hearing loss, or the reduced ability to decipher the sound source of interest from other competing sounds in a m...

What is the current status of trial NCT04513782?

This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2020-10-01. Estimated completion is 2026-05-29.

What conditions does trial NCT04513782 study?

This clinical trial studies the following conditions: Healthy Individuals, Hearing Loss, Central.

What interventions are being tested in trial NCT04513782?

The interventions under investigation include: Audiological Assessments (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT04513782?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04513782 being conducted?

This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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