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NCT04493619 · ClinicalTrials.gov registry record · Phase 1

PLX2853 as a Single Agent in Advanced Gynecological Malignancies and in Combination With Carboplatin in Platinum-Resistant Epithelial Ovarian Cancer

A Phase 1 study, sponsored by Opna Bio.

Terminated
Registry status
Phase 1
Development phase
37
Enrollment target

NCT04493619 is a Phase 1 study that was terminated before completion, run by Opna Bio. The registered enrollment target is 37 participants.

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The verdict

NCT04493619, a Phase 1 study, was terminated before completion, sponsored by Opna Bio.

TERMINATED
Registry status
Phase 1
Development phase
37 participants
Enrollment target

Study Summary

The purpose of this research study is to evaluate safety, pharmacokinetics, pharmacodynamics and preliminary efficacy of the investigational drug PLX2853 in Advanced Gynecological Malignancies with a Known ARID1A Mutation and PLX2853/Carboplatin Combination Therapy in Platinum-Resistant Epithelial Ovarian Cancer.

Interventions

  • DRUG Carboplatin
  • DRUG PLX2853

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2020-08-11
Est. Completion 2022-04-25
Phase Phase 1

Sponsor

Opna Bio

5 total trials

What the Registry Record Tells You About NCT04493619

The ClinicalTrials.gov registry entry for NCT04493619 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 37 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Opna Bio, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Carboplatin is the first listed.

NCT04493619 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04493619 about?

NCT04493619 is a clinical study titled "PLX2853 as a Single Agent in Advanced Gynecological Malignancies and in Combination With Carboplatin in Platinum-Resistant Epithelial Ovarian Cancer". The purpose of this research study is to evaluate safety, pharmacokinetics, pharmacodynamics and preliminary efficacy of the investigational drug PLX2853 in Advanced Gynecological Malignancies with a Known ARID1A Mutation and PLX2853/Carboplatin Combination Therapy in Platinum-Resistant Epithelial O...

What is the current status of trial NCT04493619?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 37 participants. The study started on 2020-08-11. Estimated completion is 2022-04-25.

What interventions are being tested in trial NCT04493619?

The interventions under investigation include: Carboplatin (DRUG), PLX2853 (DRUG).

Who is sponsoring clinical trial NCT04493619?

This trial is sponsored by Opna Bio, which has 5 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.