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NCT04489940 · ClinicalTrials.gov registry record · Phase 2

Bintrafusp Alfa in High Mobility Group AT-Hook 2 (HMGA2) Expressing Triple Negative Breast Cancer

A Phase 2 study, sponsored by EMD Serono Research & Development Institute.

Terminated
Registry status
Phase 2
Development phase
11
Enrollment target

NCT04489940 is a Phase 2 study that was terminated before completion, run by EMD Serono Research & Development Institute. The registered enrollment target is 11 participants.

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The verdict

NCT04489940, a Phase 2 study, was terminated before completion, sponsored by EMD Serono Research & Development Institute.

TERMINATED
Registry status
Phase 2
Development phase
11 participants
Enrollment target

Study Summary

The main purpose of this study was to evaluate bintrafusp alfa monotherapy in participants with triple negative breast cancer (TNBC) who express high levels of HMGA2 as determined by a centralized reverse transcriptase-polymerase chain reaction (RT-PCR) test.

Interventions

  • DRUG Bintrafusp alfa

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2020-10-12
Est. Completion 2022-07-08
Phase Phase 2

What the Registry Record Tells You About NCT04489940

The ClinicalTrials.gov registry entry for NCT04489940 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is EMD Serono Research & Development Institute, which has 81 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Bintrafusp alfa is the first listed.

NCT04489940 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04489940 about?

NCT04489940 is a clinical study titled "Bintrafusp Alfa in High Mobility Group AT-Hook 2 (HMGA2) Expressing Triple Negative Breast Cancer". The main purpose of this study was to evaluate bintrafusp alfa monotherapy in participants with triple negative breast cancer (TNBC) who express high levels of HMGA2 as determined by a centralized reverse transcriptase-polymerase chain reaction (RT-PCR) test.

What is the current status of trial NCT04489940?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 11 participants. The study started on 2020-10-12. Estimated completion is 2022-07-08.

What interventions are being tested in trial NCT04489940?

The interventions under investigation include: Bintrafusp alfa (DRUG).

Who is sponsoring clinical trial NCT04489940?

This trial is sponsored by EMD Serono Research & Development Institute, which has 81 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.