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NCT04464239 · ClinicalTrials.gov registry record · Phase 1
A Single Ascending and Repeated Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TS-142 in Healthy Participants
A Phase 1 study, sponsored by Taisho Pharmaceutical R&D.
- Completed
- Registry status
- Phase 1
- Development phase
- 28
- Enrollment target
NCT04464239: Completed Phase 1 study, sponsored by Taisho Pharmaceutical R&D.
NCT04464239 is a Phase 1 study that has completed, run by Taisho Pharmaceutical R&D. The registered enrollment target is 28 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04464239, a Phase 1 study, has completed, sponsored by Taisho Pharmaceutical R&D.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 28 participants
- Enrollment target
Study Summary
This is a study to evaluate the safety, tolerability, and pharmacokinetics of single oral doses of TS-142 compared to placebo and of a single repeated dose compared to placebo in healthy volunteers. This Phase I study is composed of two parts; Part A (Single Ascending Dose) and Part B (Repeated Dose). The study employs a randomized, double-blind, placebo-controlled, parallel group design to evaluate the single and repeat-dose safety and pharmacokinetics of TS-142 in healthy participants.
Interventions
- DRUG TS-142
- DRUG TS-142 Placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2020-09-14 |
| Est. Completion | 2021-01-21 |
| Phase | Phase 1 |
What the finished NCT04464239 record still lists
NCT04464239 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower).
The record links to 0 conditions, and to 2 interventions - of which TS-142 is the first listed.
NCT04464239 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04464239 about?
NCT04464239 is a clinical study titled "A Single Ascending and Repeated Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TS-142 in Healthy Participants". This is a study to evaluate the safety, tolerability, and pharmacokinetics of single oral doses of TS-142 compared to placebo and of a single repeated dose compared to placebo in healthy volunteers. This Phase I study is composed of two parts; Part A (Single Ascending Dose) and Part B (Repeated Dose...
What is the current status of trial NCT04464239?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2020-09-14. Estimated completion is 2021-01-21.
What interventions are being tested in trial NCT04464239?
The interventions under investigation include: TS-142 (DRUG), TS-142 Placebo (DRUG).
Who is sponsoring clinical trial NCT04464239?
This trial is sponsored by Taisho Pharmaceutical R&D, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04464239's enrollment target sits among peer trials
28 1447th of 2000 higher than 538 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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