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NCT04462198 · ClinicalTrials.gov registry record · Phase 1
Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss
A Phase 1 study, sponsored by Contineum Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 28
- Enrollment target
NCT04462198: Completed Phase 1 study, sponsored by Contineum Therapeutics.
NCT04462198 is a Phase 1 study that has completed, run by Contineum Therapeutics. The registered enrollment target is 28 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04462198, a Phase 1 study, has completed, sponsored by Contineum Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 28 participants
- Enrollment target
Study Summary
This is a randomized, double-blind study of PIPE-505, or placebo, in subjects with hearing loss associated with speech-in-noise impairment.
Primary Outcome
Number of participants with TEAEs
Interventions
- DRUG Placebo
- DRUG PIPE-505
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2020-10-15 |
| Est. Completion | 2021-06-17 |
| Phase | Phase 1 |
What the finished NCT04462198 record still lists
NCT04462198 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04462198 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04462198 about?
NCT04462198 is a clinical study titled "Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss". This is a randomized, double-blind study of PIPE-505, or placebo, in subjects with hearing loss associated with speech-in-noise impairment.
What is the current status of trial NCT04462198?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2020-10-15. Estimated completion is 2021-06-17.
What interventions are being tested in trial NCT04462198?
The interventions under investigation include: Placebo (DRUG), PIPE-505 (DRUG).
Who is sponsoring clinical trial NCT04462198?
This trial is sponsored by Contineum Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04462198's enrollment target sits among peer trials
28 1447th of 2000 higher than 538 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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