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NCT04452344 · ClinicalTrials.gov registry record · Phase 3
Opioid Analgesic Reduction Study
A Phase 3 study of Opioid Use, sponsored by Rutgers, The State University of New Jersey.
- Active
- Registry status
- Phase 3
- Development phase
- 1,815
- Enrollment target
- 5
- Study locations
NCT04452344 is a Phase 3 study of Opioid Use that is active but no longer recruiting, run by Rutgers, The State University of New Jersey. The registered enrollment target is 1,815 participants, below the 148,243-participant average among 105 other Opioid Use trials with a reported enrollment target (99% lower). The trial reports 5 study locations across 5 states.
The verdict
NCT04452344, a Phase 3 study of Opioid Use, is active but no longer recruiting, sponsored by Rutgers, The State University of New Jersey.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 1,815 participants
- Enrollment target
- 5
- Study locations
Study Summary
The goal is to provide health care professionals, including dentists, with the best possible evidence for clinical decision making when deciding upon analgesics for acute post-surgical pain management, a double-blind, stratified randomized clinical trial will be conducted to test the hypothesis that a combination of over-the-counter non-opioid containing analgesics is at least as, if not more, effective (non-inferior) than the most commonly prescribed opioid analgesic. The impacted 3rd molar extraction model will be used due to the predictable severity of the post-operative pain and generalizability of results. This double-blind, prospective, stratified, randomized pragmatic clinical trial will use the impacted 3rd molar extraction pain model.
Conditions Studied
Interventions
- DRUG opioid-containing analgesic
- DRUG two over-the-counter analgesics
Study Locations (5)
Illinois
- University of Illinois at Chicago - Chicago
Maryland
- University of Maryland - Baltimore
Michigan
- University of Michigan - Ann Arbor
New Jersey
- Rutgers School of Dental Medicine - Newark
New York
- University of Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,815 participants |
| Start Date | 2021-01-04 |
| Est. Completion | 2025-12-31 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04452344
The ClinicalTrials.gov registry entry for NCT04452344 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 1,815 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 148,243-participant average among 105 other Opioid Use trials with a reported enrollment target (99% lower). The listed sponsor is Rutgers, The State University of New Jersey, which has 413 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Opioid Use appearing as the primary indexed condition, and to 2 interventions - of which opioid-containing analgesic is the first listed.
NCT04452344 reports 5 study locations spanning 5 distinct geographic areas - top geographies include Illinois, Maryland, Michigan.
Frequently Asked Questions
What is clinical trial NCT04452344 about?
NCT04452344 is a clinical study titled "Opioid Analgesic Reduction Study". The goal is to provide health care professionals, including dentists, with the best possible evidence for clinical decision making when deciding upon analgesics for acute post-surgical pain management, a double-blind, stratified randomized clinical trial will be conducted to test the hypothesis that...
What is the current status of trial NCT04452344?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 1,815 participants. The study started on 2021-01-04. Estimated completion is 2025-12-31.
What conditions does trial NCT04452344 study?
This clinical trial studies the following conditions: Opioid Use.
What interventions are being tested in trial NCT04452344?
The interventions under investigation include: opioid-containing analgesic (DRUG), two over-the-counter analgesics (DRUG).
Who is sponsoring clinical trial NCT04452344?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04452344 being conducted?
This trial has 5 study locations across Illinois, Maryland, Michigan, New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.