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NCT04432376 · ClinicalTrials.gov registry record · Phase 2

Efficacy and Safety Study of Miconazole Oil Versus Vehicle on Fungal Infection of the Ear Canal (Otomycosis)

A Phase 2 study, sponsored by Hill Dermaceuticals.

Completed
Registry status
Phase 2
Development phase
382
Enrollment target

NCT04432376 is a Phase 2 study that has completed, run by Hill Dermaceuticals. The registered enrollment target is 382 participants.

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The verdict

NCT04432376, a Phase 2 study, has completed, sponsored by Hill Dermaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
382 participants
Enrollment target

Study Summary

This study involves two portions, a randomized, double-blind portion and an open-label portion, to evaluate the efficacy and safety of Miconazole oil 2% versus its Vehicle in the treatment of fungal infection of the outer ear canal (Otomycosis). The subjects randomized in the first portion of the study will have active fungal infection of the ear(s) and will be treated with either Miconazole Oil or the Vehicle for 14 days twice daily, 5 drops into the affected ear(s) per dose. The subjects enrolled in the open-label portion of the study may or may not have active fungal infection of the ear(s), and will be given the Miconazole Oil active drug following the same application of 5 drops into the ear(s) twice daily for 14 days. The intention of the study is to evaluate the efficacy of Miconazole Oil on fungal infection of the ears when applied using 5 drops into the ear(s) twice daily for 14 days continuously. This study also intends to show safety of Miconazole Oil 5 drops into each ear twice a day for 14 consecutive days.

Interventions

  • DRUG miconazole 2% oil
  • DRUG vehicle oil

Trial Details

FieldValue
Enrollment Target 382 participants
Start Date 2020-07-08
Est. Completion 2021-11-01
Phase Phase 2

Sponsor

Hill Dermaceuticals

4 total trials

What the Registry Record Tells You About NCT04432376

The ClinicalTrials.gov registry entry for NCT04432376 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 382 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hill Dermaceuticals, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which miconazole 2% oil is the first listed.

NCT04432376 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04432376 about?

NCT04432376 is a clinical study titled "Efficacy and Safety Study of Miconazole Oil Versus Vehicle on Fungal Infection of the Ear Canal (Otomycosis)". This study involves two portions, a randomized, double-blind portion and an open-label portion, to evaluate the efficacy and safety of Miconazole oil 2% versus its Vehicle in the treatment of fungal infection of the outer ear canal (Otomycosis). The subjects randomized in the first portion of the st...

What is the current status of trial NCT04432376?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 382 participants. The study started on 2020-07-08. Estimated completion is 2021-11-01.

What interventions are being tested in trial NCT04432376?

The interventions under investigation include: miconazole 2% oil (DRUG), vehicle oil (DRUG).

Who is sponsoring clinical trial NCT04432376?

This trial is sponsored by Hill Dermaceuticals, which has 4 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.