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NCT04419558 · ClinicalTrials.gov registry record · Phase 3

Zephyrus II: Efficacy and Safety Study of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

A Phase 3 study, sponsored by Kyntra Bio.

Terminated
Registry status
Phase 3
Development phase
372
Enrollment target

NCT04419558 is a Phase 3 study that was terminated before completion, run by Kyntra Bio. The registered enrollment target is 372 participants.

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The verdict

NCT04419558, a Phase 3 study, was terminated before completion, sponsored by Kyntra Bio.

TERMINATED
Registry status
Phase 3
Development phase
372 participants
Enrollment target

Study Summary

This is a Phase 3 trial to evaluate the efficacy and safety of 30 milligrams (mg)/kilogram (kg) intravenous (IV) infusions of pamrevlumab administered every 3 weeks as compared to placebo in participants with Idiopathic Pulmonary Fibrosis (IPF). There is a 48-week randomized treatment phase followed by an optional, open-label extension phase.

Interventions

  • DRUG Placebo
  • DRUG Pamrevlumab

Trial Details

FieldValue
Enrollment Target 372 participants
Start Date 2020-09-30
Est. Completion 2023-09-04
Phase Phase 3

Sponsor

Kyntra Bio

30 total trials

What the Registry Record Tells You About NCT04419558

The ClinicalTrials.gov registry entry for NCT04419558 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 372 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Kyntra Bio, which has 30 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04419558 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04419558 about?

NCT04419558 is a clinical study titled "Zephyrus II: Efficacy and Safety Study of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)". This is a Phase 3 trial to evaluate the efficacy and safety of 30 milligrams (mg)/kilogram (kg) intravenous (IV) infusions of pamrevlumab administered every 3 weeks as compared to placebo in participants with Idiopathic Pulmonary Fibrosis (IPF). There is a 48-week randomized treatment phase followed...

What is the current status of trial NCT04419558?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 372 participants. The study started on 2020-09-30. Estimated completion is 2023-09-04.

What interventions are being tested in trial NCT04419558?

The interventions under investigation include: Placebo (DRUG), Pamrevlumab (DRUG).

Who is sponsoring clinical trial NCT04419558?

This trial is sponsored by Kyntra Bio, which has 30 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.