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NCT04406623 · ClinicalTrials.gov registry record · Phase 1
Phase 1 Study of SL-172154 (SIRPα-Fc-CD40L) in Subjects With Ovarian Cancer
A Phase 1 study, sponsored by Shattuck Labs.
- Completed
- Registry status
- Phase 1
- Development phase
- 27
- Enrollment target
NCT04406623: Completed Phase 1 study, sponsored by Shattuck Labs.
NCT04406623 is a Phase 1 study that has completed, run by Shattuck Labs. The registered enrollment target is 27 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04406623, a Phase 1 study, has completed, sponsored by Shattuck Labs.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 27 participants
- Enrollment target
Study Summary
This is a Phase 1 first in human, open label, multi-center, dose escalation study to evaluate the safety, tolerability, PK, anti-tumor activity and pharmacodynamic effects of SL-172154 in subjects with ovarian cancer.
Primary Outcome
Number of participants with treatment emergent adverse events
Interventions
- DRUG SL-172154
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2020-06-29 |
| Est. Completion | 2023-02-02 |
| Phase | Phase 1 |
What the finished NCT04406623 record still lists
NCT04406623 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower).
The record links to 0 conditions, and to 1 intervention - of which SL-172154 is the first listed.
NCT04406623 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04406623 about?
NCT04406623 is a clinical study titled "Phase 1 Study of SL-172154 (SIRPα-Fc-CD40L) in Subjects With Ovarian Cancer". This is a Phase 1 first in human, open label, multi-center, dose escalation study to evaluate the safety, tolerability, PK, anti-tumor activity and pharmacodynamic effects of SL-172154 in subjects with ovarian cancer.
What is the current status of trial NCT04406623?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2020-06-29. Estimated completion is 2023-02-02.
What interventions are being tested in trial NCT04406623?
The interventions under investigation include: SL-172154 (DRUG).
Who is sponsoring clinical trial NCT04406623?
This trial is sponsored by Shattuck Labs, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04406623's enrollment target sits among peer trials
27 1463rd of 2000 higher than 519 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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