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NCT04390763 · ClinicalTrials.gov registry record · Phase 2

Study of Efficacy and Safety of NIS793 (With and Without Spartalizumab) in Combination With SOC Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC)

A Phase 2 study, sponsored by Novartis Pharmaceuticals.

Terminated
Registry status
Phase 2
Development phase
164
Enrollment target

NCT04390763 is a Phase 2 study that was terminated before completion, run by Novartis Pharmaceuticals. The registered enrollment target is 164 participants.

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The verdict

NCT04390763, a Phase 2 study, was terminated before completion, sponsored by Novartis Pharmaceuticals.

TERMINATED
Registry status
Phase 2
Development phase
164 participants
Enrollment target

Study Summary

The purpose of this Phase II study is to assess the efficacy and safety of NIS793 with and without spartalizumab in combination with gemcitabine/nab-paclitaxel versus gemcitabine/nab-paclitaxel in previously untreated mPDAC.

Interventions

  • DRUG nab-paclitaxel
  • DRUG gemcitabine
  • BIOLOGICAL Spartalizumab
  • BIOLOGICAL NIS793

Trial Details

FieldValue
Enrollment Target 164 participants
Start Date 2020-10-16
Est. Completion 2024-05-02
Phase Phase 2

Sponsor

Novartis Pharmaceuticals

1,375 total trials

What the Registry Record Tells You About NCT04390763

The ClinicalTrials.gov registry entry for NCT04390763 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 164 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which nab-paclitaxel is the first listed.

NCT04390763 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04390763 about?

NCT04390763 is a clinical study titled "Study of Efficacy and Safety of NIS793 (With and Without Spartalizumab) in Combination With SOC Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC)". The purpose of this Phase II study is to assess the efficacy and safety of NIS793 with and without spartalizumab in combination with gemcitabine/nab-paclitaxel versus gemcitabine/nab-paclitaxel in previously untreated mPDAC.

What is the current status of trial NCT04390763?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 164 participants. The study started on 2020-10-16. Estimated completion is 2024-05-02.

What interventions are being tested in trial NCT04390763?

The interventions under investigation include: nab-paclitaxel (DRUG), gemcitabine (DRUG), Spartalizumab (BIOLOGICAL), NIS793 (BIOLOGICAL).

Who is sponsoring clinical trial NCT04390763?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.