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NCT04387734 · ClinicalTrials.gov registry record · Phase 4
Effects of Ocrevus in Relapsing Multiple Sclerosis
A Phase 4 study of Relapsing Multiple Sclerosis, sponsored by Georgia State University.
- Active
- Registry status
- Phase 4
- Development phase
- 60
- Enrollment target
- 2
- Study locations
NCT04387734: Active Phase 4 study of Relapsing Multiple Sclerosis, sponsored by Georgia State University.
NCT04387734 is a Phase 4 study of Relapsing Multiple Sclerosis that is active but no longer recruiting, run by Georgia State University. The registered enrollment target is 60 participants, below the 2,167-participant average among 23 other Relapsing Multiple Sclerosis trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04387734, a Phase 4 study of Relapsing Multiple Sclerosis, is active but no longer recruiting, sponsored by Georgia State University.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 4
- Development phase
- 60 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this study is to test if people with relapsing multiple sclerosis (RMS) can improve ambulatory functions after one-year treatment with Ocrevus in comparison with other Disease Modifying Treatments (DMT). Sixty qualified individuals with RMS will be evenly assigned into two groups: Ocrevus and other DMT. Each group will receive the respective treatment following the FDA regulations over the one-year course. Their ambulatory functions will be assessed five times three months apart. In addition, they will receive brain MRI scans three times six months apart. Their ambulatory functions and MRI measurements will be compared between groups over time to fulfill the purposes of this study.
Primary Outcome
To quantify dynamic balance of participants during level walking.
Conditions Studied
Interventions
- DRUG Ocrelizumab
- DRUG Platform
Study Locations (2)
Georgia
- Georgia State University - Atlanta
- Multiple Sclerosis Center of Atlanta - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-02-05 |
| Est. Completion | 2026-02-28 |
| Phase | Phase 4 |
What the registry record for NCT04387734 still lists
NCT04387734 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 2,167-participant average among 23 other Relapsing Multiple Sclerosis trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Relapsing Multiple Sclerosis appearing as the primary indexed condition, and to 2 interventions - of which Ocrelizumab is the first listed.
NCT04387734 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT04387734 about?
NCT04387734 is a clinical study titled "Effects of Ocrevus in Relapsing Multiple Sclerosis". The purpose of this study is to test if people with relapsing multiple sclerosis (RMS) can improve ambulatory functions after one-year treatment with Ocrevus in comparison with other Disease Modifying Treatments (DMT). Sixty qualified individuals with RMS will be evenly assigned into two groups: Ocr...
What is the current status of trial NCT04387734?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 60 participants. The study started on 2021-02-05. Estimated completion is 2026-02-28.
What conditions does trial NCT04387734 study?
This clinical trial studies the following conditions: Relapsing Multiple Sclerosis.
What interventions are being tested in trial NCT04387734?
The interventions under investigation include: Ocrelizumab (DRUG), Platform (DRUG).
Who is sponsoring clinical trial NCT04387734?
This trial is sponsored by Georgia State University, which has 45 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04387734 being conducted?
This trial has 2 study locations across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Relapsing Multiple Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04387734's enrollment target sits among peer trials
60 22nd of 23 higher than 2 of 23 other Relapsing Multiple Sclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Relapsing Multiple Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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