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NCT04385160 · ClinicalTrials.gov registry record

Myeloproliferative Neoplasms (MPN) and COVID-19

A clinical trial, sponsored by FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS.

Completed
Registry status
552
Enrollment target

NCT04385160: Completed study, sponsored by FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS.

NCT04385160 is a clinical trial that has completed, run by FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS. The registered enrollment target is 552 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04385160 has completed, sponsored by FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS.

COMPLETED
Registry status
552 participants
Enrollment target

Study Summary

An increased risk of both venous and arterial thromboembolism was noted in reports from SARS-CoV-2-infected patients in China and has been confirmed in autopsy findings from patients who experienced sudden death. Myeloproliferative Neoplasms (MPNs), which encompass polycythemia vera, essential thrombocythemia and primary myelofibrosis, are thrombophilic disorders with a natural propensity to thrombosis that is fuelled by the intrinsic activation of inflammatory cytokines. It therefore follows that an underlying diagnosis of MPN may increase the risk of worse clinical outcomes and death during periods of active Covid-19 disease. This ambispective, observational study aims to elucidate the key factors which affect the clinical course of patients with MPN who develop Covid-19 disease.

Primary Outcome

Incidence of cases of MPN patients with COVID-19 experiencing pulmonary embolism

Trial Details

FieldValue
Enrollment Target 552 participants
Start Date 2020-05-13
Est. Completion 2022-08-31

What the finished NCT04385160 record still lists

NCT04385160 is an observational study that tracks outcomes without assigning an intervention. The registered 552 participants enrollment target is mid-sized for trials with a published cap.

The record links to 0 conditions, and to 0 interventions.

NCT04385160 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04385160 about?

NCT04385160 is a clinical study titled "Myeloproliferative Neoplasms (MPN) and COVID-19". An increased risk of both venous and arterial thromboembolism was noted in reports from SARS-CoV-2-infected patients in China and has been confirmed in autopsy findings from patients who experienced sudden death. Myeloproliferative Neoplasms (MPNs), which encompass polycythemia vera, essential throm...

What is the current status of trial NCT04385160?

This trial is currently completed. The enrollment target is 552 participants. The study started on 2020-05-13. Estimated completion is 2022-08-31.

Who is sponsoring clinical trial NCT04385160?

This trial is sponsored by FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS, which has 3 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT04385160, the US trial registry maintained by the National Library of Medicine. NCT04385160 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.