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NCT04375878 · ClinicalTrials.gov registry record · Phase 2

OPTION 2: A Trial to Assess the Safety and Efficacy of MS1819 in Enteric Capsules in Patients With Cystic Fibrosis

A Phase 2 study, sponsored by Entero Therapeutics.

Completed
Registry status
Phase 2
Development phase
27
Enrollment target

NCT04375878 is a Phase 2 study that has completed, run by Entero Therapeutics. The registered enrollment target is 27 participants.

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The verdict

NCT04375878, a Phase 2 study, has completed, sponsored by Entero Therapeutics.

COMPLETED
Registry status
Phase 2
Development phase
27 participants
Enrollment target

Study Summary

The primary objectives of this study are to assess the safety and efficacy of MS1819 in enteric capsules vs porcine pancreatic enzyme replacement therapy (PERT) in patients with exocrine pancreatic insufficiency (EPI) due to cystic fibrosis (CF). The exploratory objective of the extension phase (EP) is to find a dose of MS1819 in immediate release capsules that is safe and results in CFA values in a therapeutic range.

Interventions

  • DRUG MS1819
  • DRUG Porcine PERT

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2020-07-20
Est. Completion 2021-04-08
Phase Phase 2

Sponsor

Entero Therapeutics

7 total trials

What the Registry Record Tells You About NCT04375878

The ClinicalTrials.gov registry entry for NCT04375878 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 27 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Entero Therapeutics, which has 7 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which MS1819 is the first listed.

NCT04375878 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04375878 about?

NCT04375878 is a clinical study titled "OPTION 2: A Trial to Assess the Safety and Efficacy of MS1819 in Enteric Capsules in Patients With Cystic Fibrosis". The primary objectives of this study are to assess the safety and efficacy of MS1819 in enteric capsules vs porcine pancreatic enzyme replacement therapy (PERT) in patients with exocrine pancreatic insufficiency (EPI) due to cystic fibrosis (CF). The exploratory objective of the extension phase (EP)...

What is the current status of trial NCT04375878?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2020-07-20. Estimated completion is 2021-04-08.

What interventions are being tested in trial NCT04375878?

The interventions under investigation include: MS1819 (DRUG), Porcine PERT (DRUG).

Who is sponsoring clinical trial NCT04375878?

This trial is sponsored by Entero Therapeutics, which has 7 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.