Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04375397 · ClinicalTrials.gov registry record · Phase 2

Study of Oral Ibrutinib Capsules to Assess Respiratory Failure in Adult Participants With Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and Pulmonary Injury

A Phase 2 study, sponsored by AbbVie.

Completed
Registry status
Phase 2
Development phase
46
Enrollment target

NCT04375397 is a Phase 2 study that has completed, run by AbbVie. The registered enrollment target is 46 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04375397, a Phase 2 study, has completed, sponsored by AbbVie.

COMPLETED
Registry status
Phase 2
Development phase
46 participants
Enrollment target

Study Summary

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Lung failure is the main cause of death related to COVID-19 infection. The main objective of this study was to evaluate if ibrutinib is safe and can reduce respiratory failure in participants with COVID-19 infection.

Interventions

  • DRUG Placebo
  • DRUG Ibrutinib

Trial Details

FieldValue
Enrollment Target 46 participants
Start Date 2020-06-06
Est. Completion 2021-06-08
Phase Phase 2

Sponsor

AbbVie

526 total trials

What the Registry Record Tells You About NCT04375397

The ClinicalTrials.gov registry entry for NCT04375397 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 46 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AbbVie, which has 526 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04375397 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04375397 about?

NCT04375397 is a clinical study titled "Study of Oral Ibrutinib Capsules to Assess Respiratory Failure in Adult Participants With Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and Pulmonary Injury". Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Lung failure is the main cause of death related to COVID-19 infection. The main objective of this study was to evaluate if ibrutinib is safe and can reduce respiratory...

What is the current status of trial NCT04375397?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 46 participants. The study started on 2020-06-06. Estimated completion is 2021-06-08.

What interventions are being tested in trial NCT04375397?

The interventions under investigation include: Placebo (DRUG), Ibrutinib (DRUG).

Who is sponsoring clinical trial NCT04375397?

This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.