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NCT04371913 · ClinicalTrials.gov registry record · NA
Personalized Second Chance Breast Conservation (PSCBC): A Prospective Phase II Clinical Study
A NA study of Breast Cancer, sponsored by Weill Medical College of Cornell University.
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 3
- Study locations
NCT04371913: Recruiting NA study of Breast Cancer, sponsored by Weill Medical College of Cornell University.
NCT04371913 is a NA study of Breast Cancer that is actively recruiting participants, run by Weill Medical College of Cornell University. The registered enrollment target is 120 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (96% lower). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04371913, a NA study of Breast Cancer, is actively recruiting participants, sponsored by Weill Medical College of Cornell University.
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 3
- Study locations
Study Summary
The goal of the study is to investigate the feasibility of enabling a second chance for breast conservation in patients with in-breast recurrences after a previous lumpectomy and RT, investigators propose to test partial breast irradiation with the target volume encompassing the entire surgical bed with 1.0-1.5 cm margins. An additional goal of the study is to investigate the feasibility of enabling a second chance for breast conservation in patients with inbreast recurrences after a previous lumpectomy and PBI, the investigators propose to test whole breast RT (WBRT) with the target as the whole breast volume.
Primary Outcome
The primary endpoint of the study is to test the feasibility in terms of acute toxicity of a protocol of partial breast re-irradiation for breast cancer treatment in a previously irradiated whole breast, as defined by the rate of grade ≥ 3 treatment-related skin, fibrosis, and breast pain AEs, as graded by CTCAE version 5.0.
Conditions Studied
Interventions
- RADIATION 600cGY x 5 fractions APBI
- RADIATION 270cGy x 15 fractions WBRT
Study Locations (3)
New York
- New York Presbyterian Brooklyn Methodist Hospital - Brooklyn
- New York Presbyterian Hospital - Queens - New York
- Weill Cornell Medicine - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2020-06-30 |
| Est. Completion | 2035-12-31 |
| Phase | NA |
What NCT04371913 shows while recruiting
NCT04371913 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which 600cGY x 5 fractions APBI is the first listed.
NCT04371913 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT04371913 about?
NCT04371913 is a clinical study titled "Personalized Second Chance Breast Conservation (PSCBC): A Prospective Phase II Clinical Study". The goal of the study is to investigate the feasibility of enabling a second chance for breast conservation in patients with in-breast recurrences after a previous lumpectomy and RT, investigators propose to test partial breast irradiation with the target volume encompassing the entire surgical bed ...
What is the current status of trial NCT04371913?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2020-06-30. Estimated completion is 2035-12-31.
What conditions does trial NCT04371913 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT04371913?
The interventions under investigation include: 600cGY x 5 fractions APBI (RADIATION), 270cGy x 15 fractions WBRT (RADIATION).
Who is sponsoring clinical trial NCT04371913?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04371913 being conducted?
This trial has 3 study locations across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04371913's enrollment target sits among peer trials
120 510th of 1224 higher than 703 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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