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NCT04366440 · ClinicalTrials.gov registry record · NA
De-Implementation of Unnecessary Surgical Antibiotic Prophylaxis in Children
A NA study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 18,267
- Enrollment target
NCT04366440: Completed NA study, sponsored by Washington University School of Medicine.
NCT04366440 is a NA study that has completed, run by Washington University School of Medicine. The registered enrollment target is 18,267 participants, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (1202% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04366440, a NA study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 18,267 participants
- Enrollment target
Study Summary
The overall objective of this study is to identify the best strategy to eliminate unnecessary antibiotic use after surgery in pediatric surgical procedures considered low-risk for an SSI. Based on literature and our preliminary data suggesting surgeons will not fully accept standardized order sets based on current guidelines, the investigators hypothesize that order set modification combined with ASP facilitation will outperform standard order set modification alone in de-implementing unnecessary postoperative antibiotic use.
Primary Outcome
Clean and clean-contaminated surgical cases in children were assessed for whether they received post operative prophylaxis utilizing the Pediatric National Surgical Quality Improvement Project (NSQIP) database. A percentage was determined with the numerator being total number of clean and clean-contaminated cases receiving post operative surgical prophylaxis and the denominator is the total number of clean and clean-contaminated cases. The percentage of cases reflect the percentage of participan
Interventions
- BEHAVIORAL Order set review and modification with facilitation
- OTHER Order set review and modification
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18,267 participants |
| Start Date | 2020-11-01 |
| Est. Completion | 2024-11-30 |
| Phase | NA |
What the finished NCT04366440 record still lists
NCT04366440 is an interventional study that assigns participants to a tested intervention. Its 18,267 participants enrollment target places it among the larger protocols in the corpus, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (1202% higher).
The record links to 0 conditions, and to 2 interventions - of which Order set review and modification with facilitation is the first listed.
NCT04366440 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04366440 about?
NCT04366440 is a clinical study titled "De-Implementation of Unnecessary Surgical Antibiotic Prophylaxis in Children". The overall objective of this study is to identify the best strategy to eliminate unnecessary antibiotic use after surgery in pediatric surgical procedures considered low-risk for an SSI. Based on literature and our preliminary data suggesting surgeons will not fully accept standardized order sets b...
What is the current status of trial NCT04366440?
This trial is currently completed. It is a NA study. The enrollment target is 18,267 participants. The study started on 2020-11-01. Estimated completion is 2024-11-30.
What interventions are being tested in trial NCT04366440?
The interventions under investigation include: Order set review and modification with facilitation (BEHAVIORAL), Order set review and modification (OTHER).
Who is sponsoring clinical trial NCT04366440?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04366440's enrollment target sits among peer trials
18,267 11th of 2000 higher than 1,990 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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