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NCT04362917 · ClinicalTrials.gov registry record
Identification of β Cell Dysfunction in Relatives of Individuals With Type 1 Diabetes Mellitus
A clinical trial, sponsored by Indiana University.
- Completed
- Registry status
- 70
- Enrollment target
NCT04362917 is a clinical trial that has completed, run by Indiana University. The registered enrollment target is 70 participants.
The verdict
NCT04362917 has completed, sponsored by Indiana University.
- COMPLETED
- Registry status
- 70 participants
- Enrollment target
Study Summary
Despite the valuable information derived from older studies evaluating type 1 diabetes, the diabetes research community has, in large part, overlooked potential contributions of baseline abnormalities in β cell function to T1D development. Newer studies focusing on higher risk individuals often exclude family members without evidence of positive islet autoantibodies. New technologies to assay alternative biomarkers of β cell stress and death remain incompletely explored in both Ab negative and Ab positive family members of T1D patients. Specifically, modern biomarkers of β cell dysfunction have not been rigorously tested in combination with metabolic testing to fully understand their association with insulin secretion. The investigator's working hypothesis is that individuals at genetic risk for T1D exhibit baseline β cell dysfunction, even before development of detectable islet autoimmunity (seropositivity for islet Abs).
Interventions
- OTHER There is no intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2017-11-14 |
| Est. Completion | 2021-08-27 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04362917
The ClinicalTrials.gov registry entry for NCT04362917 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Indiana University, which has 890 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which There is no intervention is the first listed.
NCT04362917 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04362917 about?
NCT04362917 is a clinical study titled "Identification of β Cell Dysfunction in Relatives of Individuals With Type 1 Diabetes Mellitus". Despite the valuable information derived from older studies evaluating type 1 diabetes, the diabetes research community has, in large part, overlooked potential contributions of baseline abnormalities in β cell function to T1D development. Newer studies focusing on higher risk individuals often excl...
What is the current status of trial NCT04362917?
This trial is currently completed. The enrollment target is 70 participants. The study started on 2017-11-14. Estimated completion is 2021-08-27.
What interventions are being tested in trial NCT04362917?
The interventions under investigation include: There is no intervention (OTHER).
Who is sponsoring clinical trial NCT04362917?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
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