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NCT04361240 · ClinicalTrials.gov registry record
Cardiotoxicity in Breast Cancer Patients Treated With Proton or Photon Radiotherapy: A RadComp Companion Study
A clinical trial, sponsored by Abramson Cancer Center at Penn Medicine.
- Completed
- Registry status
- 172
- Enrollment target
NCT04361240: Completed study, sponsored by Abramson Cancer Center at Penn Medicine.
NCT04361240 is a clinical trial that has completed, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 172 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04361240 has completed, sponsored by Abramson Cancer Center at Penn Medicine.
- COMPLETED
- Registry status
- 172 participants
- Enrollment target
Study Summary
This is a companion study to the "Pragmatic Randomized Trial of Proton vs Photon Therapy for Patients with non-Metastatic Breast Cancer Receiving Comprehensive Nodal Radiation: A Radiotherapy Comparative Effectiveness (RadComp) Consortium Trial" (NCT02603341). The investigators will collect cardiovascular (CV) biomarkers and echocardiograms prior to, during, and for up to 1 year following radiation for a subset of patients enrolled on RadComp and to evaluate the impact of proton vs photon radiation therapy (RT) on CV function and structure.
Primary Outcome
Change in echocardiography derived LVEF from baseline
Interventions
- RADIATION Proton vs Photon Radiation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 172 participants |
| Start Date | 2020-08-01 |
| Est. Completion | 2025-05-29 |
What the finished NCT04361240 record still lists
NCT04361240 is an observational study that tracks outcomes without assigning an intervention. The registered 172 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Proton vs Photon Radiation is the first listed.
NCT04361240 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04361240 about?
NCT04361240 is a clinical study titled "Cardiotoxicity in Breast Cancer Patients Treated With Proton or Photon Radiotherapy: A RadComp Companion Study". This is a companion study to the "Pragmatic Randomized Trial of Proton vs Photon Therapy for Patients with non-Metastatic Breast Cancer Receiving Comprehensive Nodal Radiation: A Radiotherapy Comparative Effectiveness (RadComp) Consortium Trial" (NCT02603341). The investigators will collect cardiova...
What is the current status of trial NCT04361240?
This trial is currently completed. The enrollment target is 172 participants. The study started on 2020-08-01. Estimated completion is 2025-05-29.
What interventions are being tested in trial NCT04361240?
The interventions under investigation include: Proton vs Photon Radiation (RADIATION).
Who is sponsoring clinical trial NCT04361240?
This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.
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