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NCT04351438 · ClinicalTrials.gov registry record
Evaluation of Complication Rates Using Filter vs. Centrifuge and Heparin vs. Citrate Anticoagulation
A clinical trial, sponsored by University of Alabama at Birmingham.
- Completed
- Registry status
- 108
- Enrollment target
NCT04351438: Completed study, sponsored by University of Alabama at Birmingham.
NCT04351438 is a clinical trial that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 108 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04351438 has completed, sponsored by University of Alabama at Birmingham.
- COMPLETED
- Registry status
- 108 participants
- Enrollment target
Study Summary
Despite its growing use across the world, and similar efficacy, filter-based therapeutic plasma exchange (TPE) continues to be used less often that centrifuge-based TPE. One of the reasons is that the patient and circuit complications of centrifuge-based TPE are familiar to the clinical team. There is little data on the patient and circuit complications of filter-based TPE (using the Prismaflex). Furthermore, there is a reluctance to use filter-based TPE because historically, most TPE programs have used citrate-regional anticoagulation, and there is a large gap in knowledge in the use of citrate regional anti-coagulation when using filter-based TPE.
Primary Outcome
patient-related complications during procedure
Interventions
- DEVICE Active Comparator: centrifuge TPE with citrate
- DEVICE Active Comparator: Filter TPE with heparin
- DRUG Active comparator: Filter TPE with citrate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 108 participants |
| Start Date | 2012-01-01 |
| Est. Completion | 2024-02-04 |
What the finished NCT04351438 record still lists
NCT04351438 is an observational study that tracks outcomes without assigning an intervention. The registered 108 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 3 interventions - of which Active Comparator: centrifuge TPE with citrate is the first listed.
NCT04351438 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04351438 about?
NCT04351438 is a clinical study titled "Evaluation of Complication Rates Using Filter vs. Centrifuge and Heparin vs. Citrate Anticoagulation". Despite its growing use across the world, and similar efficacy, filter-based therapeutic plasma exchange (TPE) continues to be used less often that centrifuge-based TPE. One of the reasons is that the patient and circuit complications of centrifuge-based TPE are familiar to the clinical team. There ...
What is the current status of trial NCT04351438?
This trial is currently completed. The enrollment target is 108 participants. The study started on 2012-01-01. Estimated completion is 2024-02-04.
What interventions are being tested in trial NCT04351438?
The interventions under investigation include: Active Comparator: centrifuge TPE with citrate (DEVICE), Active Comparator: Filter TPE with heparin (DEVICE), Active comparator: Filter TPE with citrate (DRUG).
Who is sponsoring clinical trial NCT04351438?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
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