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NCT04336852 · ClinicalTrials.gov registry record · NA

Development of a Clinically-relevant Test for Assessment of Cerebral Vascular Function

A NA study, sponsored by University of Illinois at Chicago.

Terminated
Registry status
NA
Development phase
2
Enrollment target

NCT04336852: Clinical Trial NA study, sponsored by University of Illinois at Chicago.

NCT04336852 is a NA study that was terminated before completion, run by University of Illinois at Chicago. The registered enrollment target is 2 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04336852, a NA study, was terminated before completion, sponsored by University of Illinois at Chicago.

TERMINATED
Registry status
NA
Development phase
2 participants
Enrollment target

Study Summary

The goal of this study is to develop a test of cerebral vessel function by inducing a reactive hyperemia that will elicit a rapid and profound increase in cerebral vessel shear stress. The results of this project may lead to development of a test with prognostic/predictive utility for individual risk assessment of a future cerebrovascular event/disease. This information will be of vital importance to the medical community in regards to cerebrovascular health in aging individuals, and testing of interventions and therapies that may ameliorate these effects.

Primary Outcome

Assessment of internal carotid artery dilation and blood flow in response to a reactive hyperemic stimulus

Interventions

  • PROCEDURE Flow mediated dilation (brachial and femoral arteries)
  • PROCEDURE Cerebral vascular reactivity to carbon dioxide (CO2)
  • PROCEDURE Cerebral vascular function test

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2018-09-14
Est. Completion 2023-05-12
Phase NA
University of Illinois at Chicago

430 total trials

Why NCT04336852 stopped before completion

NCT04336852 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 3 interventions - of which Flow mediated dilation (brachial and femoral arteries) is the first listed.

NCT04336852 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04336852 about?

NCT04336852 is a clinical study titled "Development of a Clinically-relevant Test for Assessment of Cerebral Vascular Function". The goal of this study is to develop a test of cerebral vessel function by inducing a reactive hyperemia that will elicit a rapid and profound increase in cerebral vessel shear stress. The results of this project may lead to development of a test with prognostic/predictive utility for individual ris...

What is the current status of trial NCT04336852?

This trial is currently terminated. It is a NA study. The enrollment target is 2 participants. The study started on 2018-09-14. Estimated completion is 2023-05-12.

What interventions are being tested in trial NCT04336852?

The interventions under investigation include: Flow mediated dilation (brachial and femoral arteries) (PROCEDURE), Cerebral vascular reactivity to carbon dioxide (CO2) (PROCEDURE), Cerebral vascular function test (PROCEDURE).

Who is sponsoring clinical trial NCT04336852?

This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04336852's enrollment target sits among peer trials

2 1997th of 2000 the lowest of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04336852, the US trial registry maintained by the National Library of Medicine. NCT04336852 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.