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NCT04298658 · ClinicalTrials.gov registry record
The Impact of Insomnia on Pain in HIV
A clinical trial, sponsored by University of Alabama at Birmingham.
- Completed
- Registry status
- 171
- Enrollment target
NCT04298658: Completed study, sponsored by University of Alabama at Birmingham.
NCT04298658 is a clinical trial that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 171 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04298658 has completed, sponsored by University of Alabama at Birmingham.
- COMPLETED
- Registry status
- 171 participants
- Enrollment target
Study Summary
The overall objective of this application is to investigate the impact of insomnia on pain, physical functioning, and inflammation in people living with HIV. The two aims of this study to determine 1) whether insomnia promotes increased sensitivity and inflammatory reactivity to pain stimuli, and 2) if weekly fluctuations in insomnia burden drive changes in inflammation, pain severity, and physical functioning in people living with HIV. This research could help confirm insomnia as a therapeutic target for the suppression of pain and inflammation in people living with HIV.
Primary Outcome
TNF-a, IL-6, IL-12, IL-18, C-reactive protein, sCD14/163, D-dimer and IFN-gamma assays will be performed on the blood to identify levels of pro-inflammatory markers.
Interventions
- DIAGNOSTIC_TEST Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5)sleep disorders-revised
- DIAGNOSTIC_TEST Resmed ApneaLink Air device (Resmed, San Diego, CA).
- OTHER Quantitative Sensory testing (QST)
- DIAGNOSTIC_TEST OraQuick Advance Rapid HIV 1/2 Swab test
- DIAGNOSTIC_TEST Cluster of Differentiation 4 (CD4) and Viral load
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 171 participants |
| Start Date | 2020-01-01 |
| Est. Completion | 2025-07-31 |
What the finished NCT04298658 record still lists
NCT04298658 is an observational study that tracks outcomes without assigning an intervention. The registered 171 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 5 interventions - of which Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5)sleep disorders-revised is the first listed.
NCT04298658 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04298658 about?
NCT04298658 is a clinical study titled "The Impact of Insomnia on Pain in HIV". The overall objective of this application is to investigate the impact of insomnia on pain, physical functioning, and inflammation in people living with HIV. The two aims of this study to determine 1) whether insomnia promotes increased sensitivity and inflammatory reactivity to pain stimuli, and 2)...
What is the current status of trial NCT04298658?
This trial is currently completed. The enrollment target is 171 participants. The study started on 2020-01-01. Estimated completion is 2025-07-31.
What interventions are being tested in trial NCT04298658?
The interventions under investigation include: Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5)sleep disorders-revised (DIAGNOSTIC_TEST), Resmed ApneaLink Air device (Resmed, San Diego, CA). (DIAGNOSTIC_TEST), Quantitative Sensory testing (QST) (OTHER), OraQuick Advance Rapid HIV 1/2 Swab test (DIAGNOSTIC_TEST), Cluster of Differentiation 4 (CD4) and Viral load (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04298658?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
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