Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04288752 · ClinicalTrials.gov registry record · NA

Efficacy of VR101 as a Personal Lubricant

A NA study, sponsored by J3 Bioscience.

Completed
Registry status
NA
Development phase
176
Enrollment target

NCT04288752: Completed NA study, sponsored by J3 Bioscience.

NCT04288752 is a NA study that has completed, run by J3 Bioscience. The registered enrollment target is 176 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04288752, a NA study, has completed, sponsored by J3 Bioscience.

COMPLETED
Registry status
NA
Development phase
176 participants
Enrollment target

Study Summary

This Clinical Investigation (CI03) is designed to validate the efficacy of the VR101 lubricating Intravaginal Ring (IVR) as a personal lubricant device. In the proposed clinical investigation, participants will be randomized into two groups for the study, VR101 Active Ring and Inactive Ring. Participants will use VR101 active rings or inactive rings for 28 days in a randomized, double-blind, parallel group design. The study also includes an optional two-week open-label extension with active rings, and a one-week follow-up.

Primary Outcome

The Female Sexual Function Index (FSFI) is a survey validated to assess sexual function in women. The FSFI contains 19 questions, divided in to 6 characteristic domains: Desire, Arousal, Lubrication, Orgasm, Satisfaction, and Pain. Although all of these characteristics may be improved by use of a personal lubricant, only the Lubrication Domain (FSFI-LD) is directly relevant to a lubricant's intended use. Primary Endpoint: Proportion of participants that experience increased vaginal lubrication

Interventions

  • DEVICE VR101 Lubricating Intravaginal Ring
  • DEVICE Sham Ring

Trial Details

FieldValue
Enrollment Target 176 participants
Start Date 2020-02-26
Est. Completion 2020-05-26
Phase NA
J3 Bioscience

3 total trials

What the finished NCT04288752 record still lists

NCT04288752 is an interventional study that assigns participants to a tested intervention. The registered 176 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (87% lower).

The record links to 0 conditions, and to 2 interventions - of which VR101 Lubricating Intravaginal Ring is the first listed.

NCT04288752 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04288752 about?

NCT04288752 is a clinical study titled "Efficacy of VR101 as a Personal Lubricant". This Clinical Investigation (CI03) is designed to validate the efficacy of the VR101 lubricating Intravaginal Ring (IVR) as a personal lubricant device. In the proposed clinical investigation, participants will be randomized into two groups for the study, VR101 Active Ring and Inactive Ring. Partici...

What is the current status of trial NCT04288752?

This trial is currently completed. It is a NA study. The enrollment target is 176 participants. The study started on 2020-02-26. Estimated completion is 2020-05-26.

What interventions are being tested in trial NCT04288752?

The interventions under investigation include: VR101 Lubricating Intravaginal Ring (DEVICE), Sham Ring (DEVICE).

Who is sponsoring clinical trial NCT04288752?

This trial is sponsored by J3 Bioscience, which has 3 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04288752's enrollment target sits among peer trials

176 605th of 2000 higher than 1,391 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03304821 · 176 participants · Phase 2

    Granulocyte-Macrophage Stimulating Factor (GM-CSF) in Peripheral Arterial Disease

  • NCT03447938 · 176 participants · NA

    The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial

  • NCT03824145 · 176 participants · NA

    Every Day Counts: A Lifestyle Program for Women With Metastatic Breast Cancer

  • NCT04177914 · 176 participants · Phase 3

    HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04288752, the US trial registry maintained by the National Library of Medicine. NCT04288752 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.