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NCT04286451 · ClinicalTrials.gov registry record · NA
Effect of Sleep Restriction on Adipose Tissue and Skeletal Muscle Insulin Sensitivity
A NA study, sponsored by Pennington Biomedical Research Center.
- Completed
- Registry status
- NA
- Development phase
- 14
- Enrollment target
NCT04286451: Completed NA study, sponsored by Pennington Biomedical Research Center.
NCT04286451 is a NA study that has completed, run by Pennington Biomedical Research Center. The registered enrollment target is 14 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04286451, a NA study, has completed, sponsored by Pennington Biomedical Research Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 14 participants
- Enrollment target
Study Summary
Inadequate sleep is an independent risk factor for metabolic abnormalities (such as obesity, insulin resistance, and hyperglycemia). Women report sleep disruption during the menopause transition (perimenopause) and into the postmenopausal years. Sleep disruption is one of the primary reasons why midlife women seek medical care, with up to 60% reporting significant sleep disturbances (e.g., trouble falling asleep, early morning waking, and hot flashes/night sweats). Despite the majority of women experiencing sleep disruption, no study has investigated the molecular mechanisms linking sleep disruption and the changes in metabolism that coincide with menopause.
Primary Outcome
Insulin sensitivity by a 2-step hyperinsulinemic euglycemic clamp is performed at the end sleep conditions.
Interventions
- BEHAVIORAL Sleep Restriction
- BEHAVIORAL Habitual Sleep
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2020-07-28 |
| Est. Completion | 2022-04-13 |
| Phase | NA |
What the finished NCT04286451 record still lists
NCT04286451 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Sleep Restriction is the first listed.
NCT04286451 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04286451 about?
NCT04286451 is a clinical study titled "Effect of Sleep Restriction on Adipose Tissue and Skeletal Muscle Insulin Sensitivity". Inadequate sleep is an independent risk factor for metabolic abnormalities (such as obesity, insulin resistance, and hyperglycemia). Women report sleep disruption during the menopause transition (perimenopause) and into the postmenopausal years. Sleep disruption is one of the primary reasons why mid...
What is the current status of trial NCT04286451?
This trial is currently completed. It is a NA study. The enrollment target is 14 participants. The study started on 2020-07-28. Estimated completion is 2022-04-13.
What interventions are being tested in trial NCT04286451?
The interventions under investigation include: Sleep Restriction (BEHAVIORAL), Habitual Sleep (BEHAVIORAL).
Who is sponsoring clinical trial NCT04286451?
This trial is sponsored by Pennington Biomedical Research Center, which has 258 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04286451's enrollment target sits among peer trials
14 1909th of 2000 higher than 90 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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