Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04279704 · ClinicalTrials.gov registry record
Overcoming Obstacles in Epigenetic Analysis of Human Twins
A clinical trial, sponsored by Baylor College of Medicine.
- Completed
- Registry status
- 80
- Enrollment target
NCT04279704: Completed study, sponsored by Baylor College of Medicine.
NCT04279704 is a clinical trial that has completed, run by Baylor College of Medicine. The registered enrollment target is 80 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04279704 has completed, sponsored by Baylor College of Medicine.
- COMPLETED
- Registry status
- 80 participants
- Enrollment target
Study Summary
Background Cardiovascular disease is the leading cause of death in the U.S., however scientists have failed to learn fully what are the causes of this disease. A promising lead in understanding the origins of cardiovascular disease may be in gene expression changes occurring in utero in response to environmental (non-genetic) factors. Such changes govern whether a gene is turned on or turned off during an individual's lifetime. Twin pregnancies and twin infants help researchers to have a better understanding of whether the gene expression changes are genetic or environmental in origin. Therefore, the purpose of this project is to examine which body tissues (such as hair, fingernails, urine or blood) are needed to accurately study how gene activity is affected by prenatal factors.
Primary Outcome
Percent DNA methylations at metastable epialleles for each sample (urine, finger nails, peripheral blood cells, hair follicles and buccal swab).
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2016-09 |
| Est. Completion | 2020-03-01 |
What the finished NCT04279704 record still lists
NCT04279704 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 80 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT04279704 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04279704 about?
NCT04279704 is a clinical study titled "Overcoming Obstacles in Epigenetic Analysis of Human Twins". Background Cardiovascular disease is the leading cause of death in the U.S., however scientists have failed to learn fully what are the causes of this disease. A promising lead in understanding the origins of cardiovascular disease may be in gene expression changes occurring in utero in response to ...
What is the current status of trial NCT04279704?
This trial is currently completed. The enrollment target is 80 participants. The study started on 2016-09. Estimated completion is 2020-03-01.
Who is sponsoring clinical trial NCT04279704?
This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01243931 · 80 participants · NA
Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy
- NCT01659203 · 80 participants · Phase 1
Proton or Photon RT for Retroperitoneal Sarcomas
- NCT01803451 · 80 participants · Early Phase 1
Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass
- NCT01964859 · 80 participants · Phase 2
Feasibility Study for Fibroblast Autologous Skin Grafts
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia