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NCT04267003 · ClinicalTrials.gov registry record · NA

Effects of Brain Stimulation on Cognition, Oscillations and GABA Levels in Schizophrenia

A NA study of Schizophrenia, sponsored by University of California, Davis.

Recruiting
Registry status
NA
Development phase
160
Enrollment target
1
Study location

NCT04267003 is a NA study of Schizophrenia that is actively recruiting participants, run by University of California, Davis. The registered enrollment target is 160 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (27% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04267003, a NA study of Schizophrenia, is actively recruiting participants, sponsored by University of California, Davis.

RECRUITING
Registry status
NA
Development phase
160 participants
Enrollment target
1
Study location

Study Summary

People with schizophrenia often have problems with attention, learning and memory and other cognitive abilities that interfere with their work and school performance. Unfortunately, even our best treatments often do not significantly reduce these cognitive problems. The current study investigates whether or not delivering a very small electrical current to people's foreheads (called, transcranial direct current stimulation; (tDCS)) might improve functioning in the front part of the brain and reduce these cognitive problems in people with schizophrenia. tDCS is non-invasive and has been shown to improve cognitive functioning in some preliminary studies. The current study will investigate whether giving tDCS during a task is more effective than giving it during rest (Aim 1), whether delivery of tDCS to the front of the head is more effective than delivery to the back of the head (Aim 2), and whether tDCS delivery will alter levels of a major inhibitory neurotransmitter in the brain (GABA; Aim 3) that is important to cognitive functioning and may be disrupted in people with schizophrenia. Although this study is not intended to diagnose, cure or treat schizophrenia or any other disease, if results are positive it will encourage future large-scale studies to determine if tDCS can become an effective treatment for cognitive problems in people with schizophrenia.

Conditions Studied

Schizophrenia

Interventions

  • DEVICE Transcranial Direct Current Stimulation

Study Locations (1)

California

  • Imaging Research Center - Sacramento

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2020-01-09
Est. Completion 2026-08-31
Phase NA

Sponsor

University of California, Davis

657 total trials

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What the Registry Record Tells You About NCT04267003

The ClinicalTrials.gov registry entry for NCT04267003 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (27% lower). The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Schizophrenia appearing as the primary indexed condition, and to 1 intervention - of which Transcranial Direct Current Stimulation is the first listed.

NCT04267003 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT04267003 about?

NCT04267003 is a clinical study titled "Effects of Brain Stimulation on Cognition, Oscillations and GABA Levels in Schizophrenia". People with schizophrenia often have problems with attention, learning and memory and other cognitive abilities that interfere with their work and school performance. Unfortunately, even our best treatments often do not significantly reduce these cognitive problems. The current study investigates wh...

What is the current status of trial NCT04267003?

This trial is currently recruiting. It is a NA study. The enrollment target is 160 participants. The study started on 2020-01-09. Estimated completion is 2026-08-31.

What conditions does trial NCT04267003 study?

This clinical trial studies the following conditions: Schizophrenia.

What interventions are being tested in trial NCT04267003?

The interventions under investigation include: Transcranial Direct Current Stimulation (DEVICE).

Who is sponsoring clinical trial NCT04267003?

This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04267003 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.