Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04240561 · ClinicalTrials.gov registry record · NA
Characterizing Variability in Hearing Aid Outcomes in Among Older Adults With Alzheimer's Dementia
A NA study of Hearing Loss, Sensorineural and Dementia of Alzheimer Type, sponsored by Northwestern University.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 2
- Study locations
NCT04240561: Recruiting NA study of Hearing Loss, Sensorineural and Dementia of Alzheimer Type, sponsored by Northwestern University.
NCT04240561 is a NA study of Hearing Loss, Sensorineural and Dementia of Alzheimer Type that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 20 participants, below the 785-participant average among 20 other Hearing Loss, Sensorineural trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04240561, a NA study of Hearing Loss, Sensorineural and Dementia of Alzheimer Type, is actively recruiting participants, sponsored by Northwestern University.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 2
- Study locations
Study Summary
This current translational project, funded by NIH, aims to better understand the impact of various signal modification strategies for older adults with Alzheimer's dementia and its potential precursor, known as amnestic mild cognitive impairment. The investigators hypothesize that adults with Alzheimer's dementia represent an extreme case of restricted cognitive ability, such that very low working memory capacity and overall reduced cognitive capacity will limit benefit from advanced signal processing. Thus, the investigators hypothesize that adults with Alzheimer's dementia will receive greater benefit from acoustically simple, high-fidelity hearing aid processing that minimally alters the acoustic signal.
Primary Outcome
Participants will listen to and repeat recorded low-context sentences presented at conversational level at varying levels of background noise. Scoring is determined by percentage of key words in each sentence a participant is able to hear and correctly repeat back to the tester. Scores may range from 0 to 100% and a higher score indicates better understanding (i.e. a better outcome).
Conditions Studied
Interventions
- DEVICE High level of signal manipulation
- DEVICE Low level of signal manipulation
Study Locations (2)
Illinois
- Northwestern University - Chicago
- Northwestern University - Evanston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2021-07-01 |
| Est. Completion | 2025-08-31 |
| Phase | NA |
What NCT04240561 shows while recruiting
NCT04240561 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 785-participant average among 20 other Hearing Loss, Sensorineural trials with a reported enrollment target (97% lower).
The record links to 3 conditions, with Hearing Loss, Sensorineural appearing as the primary indexed condition, and to 2 interventions - of which High level of signal manipulation is the first listed.
NCT04240561 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT04240561 about?
NCT04240561 is a clinical study titled "Characterizing Variability in Hearing Aid Outcomes in Among Older Adults With Alzheimer's Dementia". This current translational project, funded by NIH, aims to better understand the impact of various signal modification strategies for older adults with Alzheimer's dementia and its potential precursor, known as amnestic mild cognitive impairment. The investigators hypothesize that adults with Alzhei...
What is the current status of trial NCT04240561?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2021-07-01. Estimated completion is 2025-08-31.
What conditions does trial NCT04240561 study?
This clinical trial studies the following conditions: Hearing Loss, Sensorineural, Dementia of Alzheimer Type, Amnestic Mild Cognitive Impairment.
What interventions are being tested in trial NCT04240561?
The interventions under investigation include: High level of signal manipulation (DEVICE), Low level of signal manipulation (DEVICE).
Who is sponsoring clinical trial NCT04240561?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04240561 being conducted?
This trial has 2 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hearing Loss, Sensorineural
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04240561's enrollment target sits among peer trials
20 19th of 20 higher than 2 of 20 other Hearing Loss, Sensorineural trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hearing Loss, Sensorineural trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Clinical Utility of Residual Hearing in the Cochlear Implant Ear
RECRUITING · NA
-
Barriers and Facilitators to OTC Hearing Aids Success
RECRUITING · NA
-
Preschool Hearing Screening
RECRUITING · NA
-
Listening Effort in Cochlear Implant Users
RECRUITING · NA
-
Reading Outcomes in Children With Vestibular Loss
RECRUITING · NA
-
Evaluation of the Automated Integration of a Robotics and ECochG System for Use With Cochlear Implant Surgery
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00573339 · 20 participants
Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing
- NCT00692939 · 20 participants · Phase 1
Autologous Stem Cell Transplantation for Crohn's Disease
- NCT00967785 · 20 participants · Phase 1
A Phase I Study of Mozobil in the Treatment of Patients With WHIMS
- NCT01406691 · 20 participants · Phase 4
Light Flashes to Treat Delayed Sleep Phase Disorder (DSPD)
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI