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NCT04205994 · ClinicalTrials.gov registry record · Early Phase 1
Dopaminergic Mechanisms Underlying Human Social Behavior
A Early Phase 1 study, sponsored by University of California, Berkeley.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 70
- Enrollment target
NCT04205994: Completed Early Phase 1 study, sponsored by University of California, Berkeley.
NCT04205994 is a Early Phase 1 study that has completed, run by University of California, Berkeley. The registered enrollment target is 70 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (32% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04205994, a Early Phase 1 study, has completed, sponsored by University of California, Berkeley.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 70 participants
- Enrollment target
Study Summary
Developing theoretical, quantitative models of the basic cognitive mechanisms underlying human social decision-making, and understanding the influence of neuromodulators such as dopamine on these mechanisms, has important ramifications for both healthy and patient populations. In this proposal the investigators combine quantitative social measures, computational models, neuroimaging, and a pharmacological intervention to define the mechanisms of social decision-making.
Primary Outcome
Subjects will make financial decisions involving themselves and another person in the context of model-based neuroeconomic games.
Interventions
- OTHER Functional Magnetic Resonance Imaging (fMRI)
- DRUG Tolcapone 200 MG
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2019-12-01 |
| Est. Completion | 2023-12-31 |
| Phase | Early Phase 1 |
What the finished NCT04205994 record still lists
NCT04205994 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (32% higher).
The record links to 0 conditions, and to 2 interventions - of which Functional Magnetic Resonance Imaging (fMRI) is the first listed.
NCT04205994 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04205994 about?
NCT04205994 is a clinical study titled "Dopaminergic Mechanisms Underlying Human Social Behavior". Developing theoretical, quantitative models of the basic cognitive mechanisms underlying human social decision-making, and understanding the influence of neuromodulators such as dopamine on these mechanisms, has important ramifications for both healthy and patient populations. In this proposal the i...
What is the current status of trial NCT04205994?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 70 participants. The study started on 2019-12-01. Estimated completion is 2023-12-31.
What interventions are being tested in trial NCT04205994?
The interventions under investigation include: Functional Magnetic Resonance Imaging (fMRI) (OTHER), Tolcapone 200 MG (DRUG).
Who is sponsoring clinical trial NCT04205994?
This trial is sponsored by University of California, Berkeley, which has 72 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04205994's enrollment target sits among peer trials
70 339th of 2000 higher than 1,647 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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