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NCT04199026 · ClinicalTrials.gov registry record · NA
Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma
A NA study of Metastatic Sarcoma and Recurrent Sarcoma, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT04199026: Recruiting NA study of Metastatic Sarcoma and Recurrent Sarcoma, sponsored by M.D. Anderson Cancer Center.
NCT04199026 is a NA study of Metastatic Sarcoma and Recurrent Sarcoma that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 20 participants, below the 40-participant average among 12 other Metastatic Sarcoma trials with a reported enrollment target (50% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04199026, a NA study of Metastatic Sarcoma and Recurrent Sarcoma, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
This early phase I trial studies the side effects of implanting and removing a microdevice in patients with sarcomas that have spread to other places in the body (metastatic) or have come back (recurrent). Microdevices are rice-sized devices that are implanted into tumor tissue and are loaded with 10 different drugs that are delivered at very small doses, or "microdoses," which may only affect a very small, local area inside the tumor. The purpose of this study is to determine which drugs delivered in the microdevice affect tumor tissue in patients with sarcomas.
Primary Outcome
Assess the safety of microdevice placement and removal in subjects undergoing resection of sarcoma.
Conditions Studied
Interventions
- DRUG Doxorubicin
- DRUG Doxorubicin Hydrochloride
- DEVICE Drug Delivery Microdevice
- DRUG Everolimus
- BIOLOGICAL Ganitumab
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-02-25 |
| Est. Completion | 2028-12-31 |
| Phase | NA |
What NCT04199026 shows while recruiting
NCT04199026 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 40-participant average among 12 other Metastatic Sarcoma trials with a reported enrollment target (50% lower).
The record links to 3 conditions, with Metastatic Sarcoma appearing as the primary indexed condition, and to 5 interventions - of which Doxorubicin is the first listed.
NCT04199026 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT04199026 about?
NCT04199026 is a clinical study titled "Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma". This early phase I trial studies the side effects of implanting and removing a microdevice in patients with sarcomas that have spread to other places in the body (metastatic) or have come back (recurrent). Microdevices are rice-sized devices that are implanted into tumor tissue and are loaded with 1...
What is the current status of trial NCT04199026?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2025-02-25. Estimated completion is 2028-12-31.
What conditions does trial NCT04199026 study?
This clinical trial studies the following conditions: Metastatic Sarcoma, Recurrent Sarcoma, Resectable Sarcoma.
What interventions are being tested in trial NCT04199026?
The interventions under investigation include: Doxorubicin (DRUG), Doxorubicin Hydrochloride (DRUG), Drug Delivery Microdevice (DEVICE), Everolimus (DRUG), Ganitumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT04199026?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04199026 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Metastatic Sarcoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04199026's enrollment target sits among peer trials
20 9th of 12 higher than 3 of 12 other Metastatic Sarcoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Metastatic Sarcoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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