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NCT04198428 · ClinicalTrials.gov registry record · NA
Clinical Decision Support for Opioid Use Disorders in Medical Settings (COMPUTE 2.0)
A NA study, sponsored by HealthPartners Institute.
- Completed
- Registry status
- NA
- Development phase
- 10,891
- Enrollment target
NCT04198428: Completed NA study, sponsored by HealthPartners Institute.
NCT04198428 is a NA study that has completed, run by HealthPartners Institute. The registered enrollment target is 10,891 participants, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (676% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04198428, a NA study, has completed, sponsored by HealthPartners Institute.
- COMPLETED
- Registry status
- NA
- Development phase
- 10,891 participants
- Enrollment target
Study Summary
Through CTN-0076-Ot (Clinical Decision Support for Opioid Use Disorders in Medical Settings: Pilot Usability Testing in an EMR (COMPUTE)), our team has iteratively developed and piloted a web-based and electronic health record (EHR)-integrated Opioid Use Disorder (OUD) Clinical Decision Support (CDS) system to offer expert guidance to primary care providers (PCPs) on the diagnosis and management of OUD. The OUD-CDS has been implemented within the EPIC EHR of one large care system and was piloted with 55 providers to ensure content validity and provider satisfaction. The team will now implement this OUD-CDS in a large multi-site clinic-randomized controlled trial to evaluate its impact on practice process measures and patient outcomes. The investigators also aim to prepare for scalability (i.e., integration into usual primary care practice after the study is complete) and dissemination by evaluating facilitators and barriers to implementation, determining the costs of implementation and maintenance, and assessing the short-term cost impacts of the OUD-CDS. The study will include three large diverse care systems and randomize a minimum of 30 clinics to receive the OUD-CDS intervention or usual care (UC). In intervention clinics, the OUD-CDS will identify patients who are at high risk for OUD or diagnosed with OUD; use data stored in the EHR for each eligible patient to assemble treatment recommendations tailored to each patient's current needs; display these recommendations to PCPs via the OUD-CDS user interface; and store analytic data from all targeted visits. In UC clinics, the OUD-CDS will run invisibly in the background to identify high-risk or OUD patients, assemble treatment recommendations tailored to each eligible patient's needs, and store analytic data from all targeted visits.
Primary Outcome
Patient has an ICD10 diagnosis code for OUD assigned at an encounter or added to the problem list
Interventions
- OTHER Opioid Wizard
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10,891 participants |
| Start Date | 2019-11-12 |
| Est. Completion | 2023-12-31 |
| Phase | NA |
What the finished NCT04198428 record still lists
NCT04198428 is an interventional study that assigns participants to a tested intervention. Its 10,891 participants enrollment target places it among the larger protocols in the corpus, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (676% higher).
The record links to 0 conditions, and to 1 intervention - of which Opioid Wizard is the first listed.
NCT04198428 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04198428 about?
NCT04198428 is a clinical study titled "Clinical Decision Support for Opioid Use Disorders in Medical Settings (COMPUTE 2.0)". Through CTN-0076-Ot (Clinical Decision Support for Opioid Use Disorders in Medical Settings: Pilot Usability Testing in an EMR (COMPUTE)), our team has iteratively developed and piloted a web-based and electronic health record (EHR)-integrated Opioid Use Disorder (OUD) Clinical Decision Support (CDS...
What is the current status of trial NCT04198428?
This trial is currently completed. It is a NA study. The enrollment target is 10,891 participants. The study started on 2019-11-12. Estimated completion is 2023-12-31.
What interventions are being tested in trial NCT04198428?
The interventions under investigation include: Opioid Wizard (OTHER).
Who is sponsoring clinical trial NCT04198428?
This trial is sponsored by HealthPartners Institute, which has 146 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04198428's enrollment target sits among peer trials
10,891 14th of 2000 higher than 1,987 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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