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NCT04195438 · ClinicalTrials.gov registry record · NA
Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy
A NA study, sponsored by University of Maryland, Baltimore.
- Completed
- Registry status
- NA
- Development phase
- 25
- Enrollment target
NCT04195438: Completed NA study, sponsored by University of Maryland, Baltimore.
NCT04195438 is a NA study that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 25 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04195438, a NA study, has completed, sponsored by University of Maryland, Baltimore.
- COMPLETED
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
Study Summary
The study will monitor carbon monoxide production in patients undergoing liver resection. Carbon monoxide will be checked from arterial blood gas obtained routinely as a part of the postoperative care as well as from the exhaled air of the patient through a CO detector commercially available and used as smokerlyzer helping people to stop smoking. The results of the surgical resection will be collected from the patient routinely ordered tests after liver resection including pathology of the resected part of the liver, laboratory and radiology tests. The study aims to identify the relationship between CO production and recovery after liver resection. Results of this study may help in predicting and improving results of liver resection.
Primary Outcome
Measure HO-1 induction by measuring endogenous CO production in relationship to the extent of hepatic resection
Interventions
- PROCEDURE CO Testing Pre/Post Hepatic Resection
- DIAGNOSTIC_TEST ABG Testing Pre/Post Hepatic Resection
- DIAGNOSTIC_TEST CT Evaluations
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2014-05-07 |
| Est. Completion | 2024-03-26 |
| Phase | NA |
What the finished NCT04195438 record still lists
NCT04195438 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 3 interventions - of which CO Testing Pre/Post Hepatic Resection is the first listed.
NCT04195438 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04195438 about?
NCT04195438 is a clinical study titled "Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy". The study will monitor carbon monoxide production in patients undergoing liver resection. Carbon monoxide will be checked from arterial blood gas obtained routinely as a part of the postoperative care as well as from the exhaled air of the patient through a CO detector commercially available and use...
What is the current status of trial NCT04195438?
This trial is currently completed. It is a NA study. The enrollment target is 25 participants. The study started on 2014-05-07. Estimated completion is 2024-03-26.
What interventions are being tested in trial NCT04195438?
The interventions under investigation include: CO Testing Pre/Post Hepatic Resection (PROCEDURE), ABG Testing Pre/Post Hepatic Resection (DIAGNOSTIC_TEST), CT Evaluations (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04195438?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04195438's enrollment target sits among peer trials
25 1712th of 2000 higher than 265 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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