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NCT04193878 · ClinicalTrials.gov registry record · Phase 3
ARrest RESpiraTory Failure From PNEUMONIA
A Phase 3 study, sponsored by Stanford University.
- Terminated
- Registry status
- Phase 3
- Development phase
- 465
- Enrollment target
NCT04193878: Clinical Trial Phase 3 study, sponsored by Stanford University.
NCT04193878 is a Phase 3 study that was terminated before completion, run by Stanford University. The registered enrollment target is 465 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04193878, a Phase 3 study, was terminated before completion, sponsored by Stanford University.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 465 participants
- Enrollment target
Study Summary
This research study seeks to establish the effectiveness of a combination of an inhaled corticosteroid and a beta agonist compared to placebo for the prevention of acute respiratory failure (ARF) in hospitalized patients with pneumonia and hypoxemia.
Primary Outcome
High flow nasal cannula (HFNC \>=20L/mon O2) and/or Noninvasive ventilation (NIV) use for greater than 36 hours OR Invasive mechanical ventilation for greater than 36 hours OR Death in a patient placed on respiratory support (HFNC, NIV, ventilator) who dies before 36 hours
Interventions
- DRUG Inhaled placebo
- DRUG Inhaled budesonide and formoterol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 465 participants |
| Start Date | 2020-06-01 |
| Est. Completion | 2025-07-22 |
| Phase | Phase 3 |
Why NCT04193878 stopped before completion
NCT04193878 is an interventional study that assigns participants to a tested intervention. The registered 465 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 2 interventions - of which Inhaled placebo is the first listed.
NCT04193878 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04193878 about?
NCT04193878 is a clinical study titled "ARrest RESpiraTory Failure From PNEUMONIA". This research study seeks to establish the effectiveness of a combination of an inhaled corticosteroid and a beta agonist compared to placebo for the prevention of acute respiratory failure (ARF) in hospitalized patients with pneumonia and hypoxemia.
What is the current status of trial NCT04193878?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 465 participants. The study started on 2020-06-01. Estimated completion is 2025-07-22.
What interventions are being tested in trial NCT04193878?
The interventions under investigation include: Inhaled placebo (DRUG), Inhaled budesonide and formoterol (DRUG).
Who is sponsoring clinical trial NCT04193878?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04193878's enrollment target sits among peer trials
465 819th of 2000 higher than 1,180 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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