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NCT04189939 · ClinicalTrials.gov registry record
Computational Psychiatric Approach to Depression
A clinical trial, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- 128
- Enrollment target
NCT04189939: Completed study, sponsored by Wake Forest University Health Sciences.
NCT04189939 is a clinical trial that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 128 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04189939 has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- 128 participants
- Enrollment target
Study Summary
The purpose of this research is to investigate how the brain changes in patients undergoing electroconvulsive (ECT) treatment for depression. Subjects will be invited to be in this study because (1) they are a patient about to receive ECT treatment for depression, or (2) they are a patient diagnosed with depression and do not qualify for ECT treatment, or (3) they are a healthy adult volunteer with no history of depression. All volunteers must be between the ages of 18-85. Participation in this research will involve three visits. Each visit will last about 3-4 hours. If the subject is a patient receiving ECT for depression the study team will schedule study visits to go along with patient treatment visits. If the subject is diagnosed with depression (not treatment-resistant depression) or are a healthy volunteer, their first visit will be scheduled at their convenience, followed by a second visit 1-3 months post visit one and a third visit 1-2 months post visit two, for a total of three research visits. Participation in this research will involve playing simple computer games while the subject's brain is scanned with magnetic resonance imaging (MRI). Additionally, the study team will assess symptoms of depression using questionnaires. Patients receiving ECT will not experience any changes to their standard of care ECT treatment plan. Healthy and non-treatment resistant depressed volunteers will not undergo ECT treatment.
Primary Outcome
neural activation measured during functional MRI
Interventions
- OTHER clinical assessments
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 128 participants |
| Start Date | 2020-03-09 |
| Est. Completion | 2023-07-10 |
What the finished NCT04189939 record still lists
NCT04189939 is an observational study that tracks outcomes without assigning an intervention. The registered 128 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which clinical assessments is the first listed.
NCT04189939 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04189939 about?
NCT04189939 is a clinical study titled "Computational Psychiatric Approach to Depression". The purpose of this research is to investigate how the brain changes in patients undergoing electroconvulsive (ECT) treatment for depression. Subjects will be invited to be in this study because (1) they are a patient about to receive ECT treatment for depression, or (2) they are a patient diagnosed...
What is the current status of trial NCT04189939?
This trial is currently completed. The enrollment target is 128 participants. The study started on 2020-03-09. Estimated completion is 2023-07-10.
What interventions are being tested in trial NCT04189939?
The interventions under investigation include: clinical assessments (OTHER).
Who is sponsoring clinical trial NCT04189939?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
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