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NCT04182113 · ClinicalTrials.gov registry record · NA

rTMS as a Probe of Episodic Memory Neurocircuitry in Schizophrenia

A NA study, sponsored by Indiana University.

Completed
Registry status
NA
Development phase
25
Enrollment target

NCT04182113 is a NA study that has completed, run by Indiana University. The registered enrollment target is 25 participants.

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The verdict

NCT04182113, a NA study, has completed, sponsored by Indiana University.

COMPLETED
Registry status
NA
Development phase
25 participants
Enrollment target

Study Summary

This will be a single site pilot study. 30 subjects with Early Phase Psychosis (EPP), defined as medical record documentation of the onset of clinically significant psychotic symptoms within the past ten years, will be enrolled. Prior to randomization (Session 1), subjects will undergo Functional Magnetic Resonance Imaging (fMRI) during Episodic Memory (EM) and Resting State (RS) paradigms. This baseline scan will also include a high-resolution structural sequence for neuronavigation purposes. Then on three separate days each occurring one-week apart, subjects will receive one session of inhibitory (1 Hertz \[Hz\]) Repetitive Transcranial Magnetic Stimulation (rTMS), one session of excitatory (20 Hz) rTMS, and one sham stimulation session targeting the precuneus. The order of the three interventions will be randomized. Immediately following each rTMS or sham session, subjects will undergo repeat fMRI during EM and RS paradigms. The investigators will also examine the effect of rTMS on EM performance.

Interventions

  • DEVICE 1 Hz rTMS Stimulation
  • DEVICE Sham rTMS Stimulation

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2019-11-08
Est. Completion 2022-06-30
Phase NA

Sponsor

Indiana University

890 total trials

What the Registry Record Tells You About NCT04182113

The ClinicalTrials.gov registry entry for NCT04182113 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Indiana University, which has 890 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which 1 Hz rTMS Stimulation is the first listed.

NCT04182113 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04182113 about?

NCT04182113 is a clinical study titled "rTMS as a Probe of Episodic Memory Neurocircuitry in Schizophrenia". This will be a single site pilot study. 30 subjects with Early Phase Psychosis (EPP), defined as medical record documentation of the onset of clinically significant psychotic symptoms within the past ten years, will be enrolled. Prior to randomization (Session 1), subjects will undergo Functional Ma...

What is the current status of trial NCT04182113?

This trial is currently completed. It is a NA study. The enrollment target is 25 participants. The study started on 2019-11-08. Estimated completion is 2022-06-30.

What interventions are being tested in trial NCT04182113?

The interventions under investigation include: 1 Hz rTMS Stimulation (DEVICE), Sham rTMS Stimulation (DEVICE).

Who is sponsoring clinical trial NCT04182113?

This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.