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NCT04172987 · ClinicalTrials.gov registry record · Phase 1
A Study of the Effect of Tirzepatide on How the Body Handles Birth Control Pills in Healthy Female Participants
A Phase 1 study, sponsored by Eli Lilly and Company.
- Completed
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
NCT04172987: Completed Phase 1 study, sponsored by Eli Lilly and Company.
NCT04172987 is a Phase 1 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04172987, a Phase 1 study, has completed, sponsored by Eli Lilly and Company.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
Study Summary
The purpose of this study is to look at how the body processes the commonly prescribed birth control pill, ethinylestradiol + norgestimate (EE/NGM), in healthy female participants and the effect of tirzepatide on how EE/NGM is processed by the body. Information about any side effects that may occur will also be collected. Screening is required within 28 days prior to the start of the study. For each participant, the study will last about 20 weeks, including screening.
Primary Outcome
Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve (AUC) Within 1 Dosing Interval (AUC\[0-tau\]) of Ethinylestradiol (EE)
Interventions
- DRUG Tirzepatide
- DRUG EE/NGM
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2020-02-26 |
| Est. Completion | 2021-02-09 |
| Phase | Phase 1 |
What the finished NCT04172987 record still lists
NCT04172987 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).
The record links to 0 conditions, and to 2 interventions - of which Tirzepatide is the first listed.
NCT04172987 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04172987 about?
NCT04172987 is a clinical study titled "A Study of the Effect of Tirzepatide on How the Body Handles Birth Control Pills in Healthy Female Participants". The purpose of this study is to look at how the body processes the commonly prescribed birth control pill, ethinylestradiol + norgestimate (EE/NGM), in healthy female participants and the effect of tirzepatide on how EE/NGM is processed by the body. Information about any side effects that may occur ...
What is the current status of trial NCT04172987?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2020-02-26. Estimated completion is 2021-02-09.
What interventions are being tested in trial NCT04172987?
The interventions under investigation include: Tirzepatide (DRUG), EE/NGM (DRUG).
Who is sponsoring clinical trial NCT04172987?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04172987's enrollment target sits among peer trials
40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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